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加纳丙型肝炎病毒感染快速诊断检测阳性率。

The prevalence of positive rapid diagnostic test of hepatitis C virus infection in Ghana.

机构信息

Polyclinic, Iranian Red Crescent Society, Accra, Ghana.

Hearing Disorders Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Pan Afr Med J. 2020 Aug 21;36:322. doi: 10.11604/pamj.2020.36.322.22490. eCollection 2020.

Abstract

INTRODUCTION

hepatitis C virus (HCV) infection is one of the most common viral hepatitis in Africa. Rapid diagnostic test (RDT) is a useful tool to identify antibody anti-HCV in point of care. In this study, we decided to determine prevalence of cases with positive rapid diagnostic test of HCV infection.

METHODS

this cross-sectional study was conducted in a polyclinic, Accra, Ghana. Using convenience sampling, 728 participants were screened with blood-based RDT and interviewed about personal risk behaviors for transmission of HCV. Data was entered in SPSS version 18 and analyzed.

RESULTS

there was 1.6% positive RDT in our participants. The mean age of them was 29.58 ± 12.31 years old that were younger than the participants with negative RDT (p: 0.027). The rate of positive test was 66.67% in women and 33.33% in men. There was a negative association between age and RDT positive (aOR: 0.91, 95%CI 0.85-0.96). The odds of positive RDT in married participants was 6.32 fold others after adjusting model (p: 0.014). There were no important risk behavior for HCV, except one person with history of contacting blood or needles.

CONCLUSION

the risk of positive RDT has a reverse relationship with aging and also it has an increase in married individuals. Therefore preventive education and screening for HCV should be a priority in young and middle-aged adults because of more sexual activity.

摘要

简介

丙型肝炎病毒(HCV)感染是非洲最常见的病毒性肝炎之一。快速诊断检测(RDT)是一种在护理点识别抗 HCV 抗体的有用工具。在这项研究中,我们决定确定 HCV 感染快速诊断检测阳性病例的患病率。

方法

这是一项在加纳阿克拉的一个门诊部进行的横断面研究。使用便利抽样,对 728 名参与者进行了基于血液的 RDT 筛查,并对他们的 HCV 传播个人风险行为进行了访谈。数据输入 SPSS 版本 18 并进行分析。

结果

我们的参与者中 RDT 阳性率为 1.6%。他们的平均年龄为 29.58 ± 12.31 岁,比 RDT 阴性的参与者年轻(p:0.027)。女性的阳性检测率为 66.67%,男性为 33.33%。年龄与 RDT 阳性之间呈负相关(aOR:0.91,95%CI 0.85-0.96)。调整模型后,已婚参与者的 RDT 阳性几率是其他人的 6.32 倍(p:0.014)。除了一名有接触血液或针头史的人外,没有 HCV 的重要风险行为。

结论

RDT 阳性的风险与年龄呈负相关,在已婚人群中也呈上升趋势。因此,由于性行为更为活跃,针对 HCV 的预防教育和筛查应该是年轻和中年成年人的优先事项。

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