Polyclinic, Iranian Red Crescent Society, Accra, Ghana.
Hearing Disorders Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pan Afr Med J. 2020 Aug 21;36:322. doi: 10.11604/pamj.2020.36.322.22490. eCollection 2020.
hepatitis C virus (HCV) infection is one of the most common viral hepatitis in Africa. Rapid diagnostic test (RDT) is a useful tool to identify antibody anti-HCV in point of care. In this study, we decided to determine prevalence of cases with positive rapid diagnostic test of HCV infection.
this cross-sectional study was conducted in a polyclinic, Accra, Ghana. Using convenience sampling, 728 participants were screened with blood-based RDT and interviewed about personal risk behaviors for transmission of HCV. Data was entered in SPSS version 18 and analyzed.
there was 1.6% positive RDT in our participants. The mean age of them was 29.58 ± 12.31 years old that were younger than the participants with negative RDT (p: 0.027). The rate of positive test was 66.67% in women and 33.33% in men. There was a negative association between age and RDT positive (aOR: 0.91, 95%CI 0.85-0.96). The odds of positive RDT in married participants was 6.32 fold others after adjusting model (p: 0.014). There were no important risk behavior for HCV, except one person with history of contacting blood or needles.
the risk of positive RDT has a reverse relationship with aging and also it has an increase in married individuals. Therefore preventive education and screening for HCV should be a priority in young and middle-aged adults because of more sexual activity.
丙型肝炎病毒(HCV)感染是非洲最常见的病毒性肝炎之一。快速诊断检测(RDT)是一种在护理点识别抗 HCV 抗体的有用工具。在这项研究中,我们决定确定 HCV 感染快速诊断检测阳性病例的患病率。
这是一项在加纳阿克拉的一个门诊部进行的横断面研究。使用便利抽样,对 728 名参与者进行了基于血液的 RDT 筛查,并对他们的 HCV 传播个人风险行为进行了访谈。数据输入 SPSS 版本 18 并进行分析。
我们的参与者中 RDT 阳性率为 1.6%。他们的平均年龄为 29.58 ± 12.31 岁,比 RDT 阴性的参与者年轻(p:0.027)。女性的阳性检测率为 66.67%,男性为 33.33%。年龄与 RDT 阳性之间呈负相关(aOR:0.91,95%CI 0.85-0.96)。调整模型后,已婚参与者的 RDT 阳性几率是其他人的 6.32 倍(p:0.014)。除了一名有接触血液或针头史的人外,没有 HCV 的重要风险行为。
RDT 阳性的风险与年龄呈负相关,在已婚人群中也呈上升趋势。因此,由于性行为更为活跃,针对 HCV 的预防教育和筛查应该是年轻和中年成年人的优先事项。