在连续五个季节（2013-2018 年）中，在加泰罗尼亚（西班牙）的一家三级医院对人类呼吸道合胞病毒 A 和 B 进行病毒学监测。
Virological surveillance of human respiratory syncytial virus A and B at a tertiary hospital in Catalonia (Spain) during five consecutive seasons (2013-2018).
机构信息
Respiratory Virus Unit, Microbiology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.
Paediatric Hospitalisation Unit, Department of Paediatrics, Hospital Universitari Maternoinfantil Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
出版信息
Future Microbiol. 2019 Mar;14:373-381. doi: 10.2217/fmb-2018-0261. Epub 2019 Mar 12.
AIM
Human respiratory syncytial virus (HRSV) is the main cause of respiratory tract infections among infants.
MATERIALS & METHODS: In the present study, the molecular epidemiology of HRSV detected from 2013 to 2017 has been described.
RESULTS
A 10% of collected samples were laboratory confirmed for HRSV. Patients under 2 years of age were the main susceptible population to respiratory syncytial virus disease, but an increasingly number of confirmed patients over 65 years of age was reported. Epidemics usually started in autumn and ended in spring. Both HRSV groups co-circulated every season, but the HRSV-B was the most predominant. HRSV-A and HRSV-B strains mainly belonged to ON1 and BA9 genotypes, respectively.
CONCLUSION
The present study reports recent data about the genetic diversity of circulating HRSV in Spain.
目的
人呼吸道合胞病毒（HRSV）是导致婴儿呼吸道感染的主要病原体。
材料与方法
本研究描述了 2013 年至 2017 年期间检测到的 HRSV 的分子流行病学情况。
结果
10%的采集样本经实验室确认为 HRSV 阳性。2 岁以下的患者是呼吸道合胞病毒疾病的主要易感人群，但报告的 65 岁以上确诊患者数量不断增加。流行通常始于秋季，止于春季。两种 HRSV 组在每个季节都同时流行，但 HRSV-B 是最主要的流行株。HRSV-A 和 HRSV-B 株主要分别属于 ON1 和 BA9 基因型。
结论
本研究报告了西班牙流行的 HRSV 遗传多样性的最新数据。
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