Savchenko O N, Danilova O A, Proimina F I, Maslova L N, Serova L I
Fiziol Zh SSSR Im I M Sechenova. 1986 Mar;72(3):311-5.
After complete deafferentation of the mediobasal hypothalamus in male rats, the luteinizing hormone content increased in the blood which correlated with an increasing of testosterone secretion, weight of seminal glands and additional sexual organs. Half of the operated animals preserve copulating ability. The content of folliculo-stimulating hormone in the blood of animals after the complete deafferentation was decreased, particularly in non-copulating males. After the interior deafferentation of the mediobasal hypothalamus in the rats, the luteinizing hormone and testosterone contents in the blood did not change but the weight of seminal glands and concentration of folliculo-stimulating hormone in the blood decreased. The data obtained suggest different mechanisms of control of the luteinizing and folliculo-stimulating hormones secretion in male rats, the connection of the mediobasal hypothalamus with anterior hypothalamus and preoptic area being necessary for normal secretion of the folliculo-stimulating hormone.
对雄性大鼠的下丘脑内侧基部进行完全去传入神经支配后，血液中促黄体生成素含量增加，这与睾酮分泌增加、精囊及附属性器官重量增加相关。半数手术动物保留交配能力。完全去传入神经支配后动物血液中促卵泡刺激素含量降低，尤其在无交配能力的雄性动物中。对大鼠下丘脑内侧基部进行内侧去传入神经支配后，血液中促黄体生成素和睾酮含量未变，但精囊重量及血液中促卵泡刺激素浓度降低。所获数据表明雄性大鼠促黄体生成素和促卵泡刺激素分泌的调控机制不同，下丘脑内侧基部与下丘脑前部及视前区的联系对于促卵泡刺激素的正常分泌是必要的。
