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乳腺癌脑转移可能对内分泌治疗有反应：两例报告。

Brain metastases from breast cancer may respond to endocrine therapy: report of two cases.

作者信息

Wang Qian, Sun Bing, Liu Chao, Shi Sanzhong, Ding Lijuan, Liu Jiannan, Wu Shikai

机构信息

Department of Radiation Oncology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, China,

出版信息

Onco Targets Ther. 2019 Feb 19;12:1389-1393. doi: 10.2147/OTT.S188143. eCollection 2019.

DOI:10.2147/OTT.S188143
PMID:30863105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6389012/
Abstract

Brain metastases from breast cancer have a poor prognosis. There have been few cases reported where patients with breast cancer and brain metastases respond well to endocrine therapy (tamoxifen or letrozole). Here, we report the cases of two breast cancer patients with brain metastases who responded to medroxyprogesterone acetate and fulvestrant, respectively. These cases indicate that endocrine therapy could be very effective in the management of brain metastases from breast carcinoma.

摘要

乳腺癌脑转移预后较差。鲜有报道称乳腺癌合并脑转移患者对内分泌治疗（他莫昔芬或来曲唑）反应良好的病例。在此，我们报告了两例分别对醋酸甲羟孕酮和氟维司群有反应的乳腺癌脑转移患者的病例。这些病例表明，内分泌治疗在乳腺癌脑转移的治疗中可能非常有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/765e/6389012/d0d1075890f7/ott-12-1389Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/765e/6389012/22f42909fef3/ott-12-1389Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/765e/6389012/d0d1075890f7/ott-12-1389Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/765e/6389012/22f42909fef3/ott-12-1389Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/765e/6389012/d0d1075890f7/ott-12-1389Fig2.jpg

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