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2
Use of a dermal regeneration template and full-thickness skin grafts to reconstruct exposed bone in the head and neck.使用真皮再生模板和全厚皮片重建头颈部外露骨。
Br J Oral Maxillofac Surg. 2016 Dec;54(10):1123-1125. doi: 10.1016/j.bjoms.2016.03.004. Epub 2016 Mar 19.
3
Exposed tibial bone after burns: Flap reconstruction versus dermal substitute.烧伤后胫骨外露:皮瓣重建与真皮替代物对比
Burns. 2016 Mar;42(2):e31-7. doi: 10.1016/j.burns.2015.08.013. Epub 2015 Sep 12.
4
Novel Use of Synthetic Acellular Dermal Matrix for Coverage of a Tibial Defect Following Resection of an Osteochondroma: A Case Report.合成脱细胞真皮基质在骨软骨瘤切除术后胫骨缺损覆盖中的新应用:一例报告
Int J Low Extrem Wounds. 2016 Mar;15(1):82-5. doi: 10.1177/1534734615604279. Epub 2015 Sep 8.
5
Effect of amniotic membrane on graft take in extremity burns.羊膜对肢体烧伤植皮成活率的影响。
Burns. 2013 Sep;39(6):1137-41. doi: 10.1016/j.burns.2013.01.017. Epub 2013 Mar 21.
6
The treatment of bone exposure in burns by using artificial dermis.使用人工真皮治疗烧伤中的骨外露。
Ann Plast Surg. 2012 Dec;69(6):607-10. doi: 10.1097/SAP.0b013e318273f845.
7
Effect of fresh human amniotic membrane dressing on graft take in patients with chronic burn wounds compared with conventional methods.新鲜人羊膜敷料对慢性烧伤创面植皮成活率的影响与传统方法比较。
Burns. 2013 Mar;39(2):349-53. doi: 10.1016/j.burns.2012.07.010. Epub 2012 Aug 27.
8
Use of acellular dermal replacement in reconstruction of nonhealing lower extremity wounds.脱细胞真皮替代物在下肢难愈伤口重建中的应用。
J Burn Care Res. 2011 Jan-Feb;32(1):124-8. doi: 10.1097/BCR.0b013e318204b327.
9
The use of a dermal substitute and thin skin grafts in the cure of "complex" leg ulcers.使用真皮替代物和薄皮移植治疗“复杂型”腿部溃疡。
Dermatol Surg. 2009 Feb;35(2):195-200. doi: 10.1111/j.1524-4725.2008.34409.x.
10
Integra in lower extremity reconstruction after burn injury.Integra用于烧伤后下肢重建。
Plast Reconstr Surg. 2008 Apr;121(4):1256-1262. doi: 10.1097/01.prs.0000304237.54236.66.

双下肢三度烧伤:采用真皮再生基质进行下肢挽救治疗。

Bilateral third-degree burn of the legs: lower limb salvage with dermal regenerative matrix.

作者信息

Ribeiro L M, Serras R, Guimarães D, Vilela M, Mouzinho M M

机构信息

Hospital São José (Centro Hospitalar Lisboa Central), Lisbon, Portugal.

出版信息

Ann Burns Fire Disasters. 2018 Sep 30;31(3):228-232.

PMID:30863258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6367860/
Abstract

Third-degree burns of the lower extremities are among the most difficult burn injuries to treat as they frequently expose bone, tendons or articular surfaces. Coverage with a flap is the ideal treatment, but local tissue is often unavailable, and free flaps require sophisticated equipment and perfect microsurgical technique. We demonstrate a treatment option to obtain a stable cutaneous coverage for this kind of injury, consisting in an association of skin grafts, amniotic membrane and bilaminar dermal matrix templates. This combined treatment proved to be an excellent option to cover a wide area of tibial exposure with low donor site morbidity and good functional and aesthetic results. This shows that artificial dermis is a good alternative for treating bone exposure, especially in patients for whom a classic flap reconstruction is not suitable.

摘要

下肢三度烧伤是最难治疗的烧伤之一,因为它们经常暴露骨骼、肌腱或关节表面。皮瓣覆盖是理想的治疗方法,但局部组织往往无法使用,而游离皮瓣需要精密的设备和精湛的显微外科技术。我们展示了一种针对此类损伤获得稳定皮肤覆盖的治疗方案,该方案包括皮肤移植、羊膜和双层真皮基质模板联合使用。这种联合治疗被证明是覆盖大面积胫骨外露的极佳选择,供区发病率低,功能和美学效果良好。这表明人工真皮是治疗骨外露的良好替代方案,特别是对于不适合经典皮瓣重建的患者。