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继发于与巨大卵巢肿瘤相关的盆腔血栓形成的肺血栓栓塞症。

Pulmonary thromboembolism secondary to pelvic thrombosis related to giant ovarian tumor.

作者信息

Amadasi Alberto, Andreola Salvatore, Bianchi Marta, Boracchi Michele, Gentile Guendalina, Maciocco Francesca, Marchesi Matteo, Zoja Riccardo

机构信息

Università degli Studi di Milano, Dipartimento di Scienze Biomediche per la Salute, Sezione di Medicina Legale e delle Assicurazioni. Milano, Italy.

Azienda Socio Sanitaria Papa Giovanni XXIII, Ospedale di Bergamo. Bergamo, Italy.

出版信息

Autops Case Rep. 2019 Jan 14;9(1):e2018061. doi: 10.4322/acr.2018.061. eCollection 2019 Jan-Mar.

Abstract

Pulmonary thromboembolism (PTE) is one of the major complications in oncologic patients. The incidence of PTE in these cases is 4 to 7 times higher than in non-oncologic patients. Ovarian tumors, specifically those of large sizes, may impair the blood flow through the pelvic veins as tumor pressure over the pelvic vessels increases the incidence of thrombosis. The authors report the case of the unexpected death of a 74-year-old female due to massive pulmonary thromboembolism, associated with an ovarian tumor almost of 15 kg of weight that filled the abdominal and pelvic cavities. The compressive effect on the walls of the pudendal and periuterine veins somehow facilitated the local thrombosis. According to the histological characterization on post-mortem samples, the mass was identified as an "atypical proliferative (borderline) mucinous tumor." The case emphasizes the important association between pulmonary thromboembolism and ovarian tumors.

摘要

肺血栓栓塞症(PTE)是肿瘤患者的主要并发症之一。这些患者中PTE的发病率比非肿瘤患者高4至7倍。卵巢肿瘤,特别是那些体积较大的肿瘤,可能会因肿瘤对盆腔血管的压迫导致盆腔静脉血流受阻,从而增加血栓形成的发生率。作者报告了一例74岁女性因大面积肺血栓栓塞意外死亡的病例,该患者伴有一个重达15公斤、占据腹腔和盆腔的卵巢肿瘤。肿瘤对阴部静脉和子宫周围静脉壁的压迫在一定程度上促成了局部血栓形成。根据尸检样本的组织学特征,该肿块被鉴定为“非典型增生性(交界性)黏液性肿瘤”。该病例强调了肺血栓栓塞症与卵巢肿瘤之间的重要关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c511/6394364/34ecb457c574/autopsy-09-01e2018061-g01.jpg

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