Lee Chia-Yi, Chen Hung-Ta, Hsueh Yi-Jen, Chen Hung-Chi, Huang Chieh-Cheng, Meir Yaa-Jyuhn James, Cheng Chao-Min, Wu Wei-Chi
Department of Ophthalmology, Show Chwan Memorial Hospital, Changhua 50093, Taiwan.
Department of Internal Medicine, Taipei City Hospital- Heping Branch, Taipei 10341, Taiwan.
World J Clin Cases. 2019 Mar 6;7(5):642-649. doi: 10.12998/wjcc.v7.i5.642.
The current case report describes successful phacoemulsification with the aid of perioperative topical ascorbic acid (AA) in two patients with corneal endothelial disorders to prevent postoperative corneal endothelial decompensation.
Two eyes of two patients underwent phacoemulsification with pre-existing corneal endothelial disorders including Fuchs corneal endothelial dystrophy (Patient 1) and endotheliitis (Patient 2). Topical AA was applied to both patients at least one month before and after with a frequency of four times per day. After the surgery, both eyes improved best-corrected visual acuity (BCVA) and there was limited human corneal endothelial cell loss without signs of corneal endothelial decompensation, such as deteriorated BCVA or persistent corneal edema during the follow-up of at least two years.
Perioperative administration of topical AA may be an alternative therapy to the triple procedure in patients expecting to undergo cataract surgery.
本病例报告描述了在两名患有角膜内皮疾病的患者中，借助围手术期局部应用抗坏血酸（AA）成功进行超声乳化白内障吸除术，以预防术后角膜内皮失代偿。
两名患者的两只眼睛接受了超声乳化白内障吸除术，术前存在角膜内皮疾病，包括富克斯角膜内皮营养不良（患者1）和内皮炎（患者2）。两名患者在手术前后至少一个月每天四次局部应用AA。术后，两只眼睛的最佳矫正视力（BCVA）均有所改善，在至少两年的随访期间，人角膜内皮细胞损失有限，且无角膜内皮失代偿迹象，如BCVA恶化或持续性角膜水肿。
对于预期进行白内障手术的患者，围手术期局部应用AA可能是三联手术的替代疗法。
Zotero 插件
