Turgay Yildirim Özge, Akşit Ercan, Aydin Fatih, Hüseyinoğlu Aydin Ayşe
Department of Cardiology, Eskisehir State Hospital, Eskisehir.
Department of Cardiology, Canakkale Onsekiz Mart University, Çanakkale, Turkey.
Blood Coagul Fibrinolysis. 2019 Apr;30(3):96-103. doi: 10.1097/MBC.0000000000000801.
: Left ventricular thrombus (LVT) is a commonly seen complication of myocardial infarction and it also can be seen because of hypertrophic cardiomyopathies, nonischemic dilated cardiomyopathies, malignancies, and so on. Guidelines suggest the use of warfarin for left ventricular thrombi, but recent case reports show that direct oral anticoagulants (DOACs) are beginning to be used for this complication. DOACs are strong alternatives for warfarin because of their efficacy and safety even though there is no randomized controlled trial that proves the effect of DOACs against LVT. In this article, we gather the case reports of DOACs against left ventricular thrombi in various conditions.
左心室血栓（LVT）是心肌梗死常见的并发症，也可见于肥厚型心肌病、非缺血性扩张型心肌病、恶性肿瘤等。指南建议使用华法林治疗左心室血栓，但近期病例报告显示，直接口服抗凝剂（DOACs）也开始用于治疗该并发症。尽管尚无随机对照试验证明DOACs对LVT的疗效，但因其有效性和安全性，DOACs是华法林的有力替代药物。在本文中，我们收集了在各种情况下使用DOACs治疗左心室血栓的病例报告。
