Hu Zunfu, Yin Yongheng, Liu Qingyun, Zheng Xiuwen
Linyi University, Linyi, Shandong, China.
Analyst. 2019 Apr 8;144(8):2716-2724. doi: 10.1039/c9an00307j.
The rapid and sensitive detection of H2O2 is of great importance for a series of industries. In this work, surface-modified FePt nanoparticles were loaded into metal-organic frameworks (MOFs, MIL-101(Fe)) in a facile in situ way and the resulting material (FePt@MOFs NCs) acted as a high efficient colorimetric detection agent. The as-prepared FePt@MOFs NCs possess a well-defined octahedron shape and high stability in water. Via the oxidation reaction of the chromogenic substrate 4,4'-bi-2,6-xylidine, the obtained FePt@MOFs NCs were proved to possess prominent peroxidase-mimic activity. Under the most favorable conditions, the linear range for H2O2 detection was 40 μM to 800 μM and the detection limit was 18.9 μM. Furthermore, FePt@MOFs NCs were successfully applied to the detection of H2O2 in real samples such as fruit juice. The developed colorimetric sensing platform is expected to have potential for the exact detection of H2O2 for the food, mining and bio-pharmaceutical industries, due to its high stability, sensitivity, rapidness and easy preparation.
H2O2的快速灵敏检测对一系列行业至关重要。在这项工作中，表面改性的FePt纳米颗粒以简便的原位方式负载到金属有机框架（MOF，MIL-101(Fe)）中，所得材料（FePt@MOFs NCs）作为高效的比色检测剂。所制备的FePt@MOFs NCs具有明确的八面体形状且在水中具有高稳定性。通过发色底物4,4'-联-2,6-二甲基苯胺的氧化反应，证明所获得的FePt@MOFs NCs具有显著的过氧化物酶模拟活性。在最有利的条件下，H2O2检测的线性范围为40 μM至800 μM，检测限为18.9 μM。此外，FePt@MOFs NCs成功应用于果汁等实际样品中H2O2的检测。所开发的比色传感平台因其高稳定性、灵敏度、快速性和易于制备，有望在食品、采矿和生物制药行业中对H2O2进行准确检测方面具有潜力。
