抑郁症患者催乳素对促甲状腺激素释放激素的反应

Prolactin response to TRH in depression.

作者信息

Zis A P, Albala A A, Haskett R F, Carroll B J, Lohr N E

出版信息

J Psychiatr Res. 1986;20(1):77-82. doi: 10.1016/0022-3956(86)90025-7.

Abstract

We studied the prolactin response to TRH in 53 unmedicated psychiatric inpatients. The prolactin response of females was significantly greater than the response of male subjects. There was no significant difference in the prolactin response to TRH between depressed patients and those with other psychiatric diagnoses. There was no significant relationship between the prolactin response to TRH and the severity of depression, the TSH response to TRH or the resistance to suppression of cortisol secretion by dexamethasone.

摘要

我们研究了53名未接受药物治疗的精神科住院患者对促甲状腺激素释放激素（TRH）的催乳素反应。女性的催乳素反应显著大于男性受试者的反应。抑郁症患者与其他精神科诊断患者对TRH的催乳素反应无显著差异。对TRH的催乳素反应与抑郁症严重程度、对TRH的促甲状腺激素反应或地塞米松对皮质醇分泌抑制的抵抗之间无显著关系。