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妊娠期心尖球形综合征:病例报告及文献复习。

Takotsubo cardiomyopathy in pregnancy: a case report and literature review.

机构信息

Department of Obstetrics and Gynecology, Aga Khan University, P.O. Box 30270-00100, Nairobi, Kenya.

Department of Pulmonary and Critical Care Medicine, Norwalk Hospital/Yale University, Norwalk, CT, USA.

出版信息

BMC Pregnancy Childbirth. 2019 Mar 12;19(1):89. doi: 10.1186/s12884-019-2233-7.

Abstract

BACKGROUND

Takotsubo cardiomyopathy is rare in pregnancy and is characterized by left ventricular dysfunction with apical ballooning. This transient cardiac dysfunction may affect women of childbearing age in the antepartum, intrapartum or postpartum period. Most patients respond well to medical management with resolution of cardiac dysfunction within weeks.

CASE PRESENTATION

A 35-year-old female in her second pregnancy presented with severe preeclampsia at 31 weeks of gestation. She subsequently developed severe substernal chest pain and workup showed a stress induced cardiomyopathy prior to her delivery via caesarean section. She had full recovery of her cardiac function by 12 weeks postpartum after medical management.

CONCLUSIONS

Stress induced cardiomyopathy, though rare, should be considered after acute myocardial infarction has been ruled out in gravid females presenting with acute chest pain. Management should involve a multidisciplinary team. Cardiac function recovery is common within 4 weeks although some patients may require long term heart failure management.

摘要

背景

Takotsubo 心肌病在妊娠中较为罕见,其特征为左心室功能障碍伴心尖球囊样变。这种短暂性的心脏功能障碍可能会影响育龄期妇女的产前、产时或产后。大多数患者经药物治疗后心脏功能障碍可在数周内得到缓解。

病例介绍

一名 35 岁的女性处于第二次妊娠,孕 31 周时出现严重子痫前期。随后,她出现严重胸骨后疼痛,经检查发现她在剖宫产前发生应激性心肌病。经药物治疗后,她在产后 12 周时心脏功能完全恢复。

结论

在排除育龄期女性急性胸痛为急性心肌梗死后,应考虑应激性心肌病。管理应涉及多学科团队。尽管一些患者可能需要长期心力衰竭管理,但心脏功能恢复通常在 4 周内。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc84/6416971/47166954ba8d/12884_2019_2233_Fig1_HTML.jpg

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