硫酸镍对黑腹果蝇的致突变性。

Mutagenicity of nickel sulphate in Drosophila melanogaster.

作者信息

Rodríguez-Arnaiz R, Ramos P

出版信息

Mutat Res. 1986 Jun;170(3):115-7. doi: 10.1016/0165-1218(86)90023-6.

Abstract

Nickel sulphate was injected into Drosophila melanogaster males at different concentrations in order to test the chemical for the induction of SLRL and SCL in germ cells. Nickel sulphate induced SLRL at concentrations tested, with the peak of activity at premeiotic and postmeiotic stages. It failed to produce SCL except at the highest concentration tested, where induction of XO males was significant for the pooled data.

摘要

将不同浓度的硫酸镍注射到雄性黑腹果蝇体内，以测试该化学物质对生殖细胞中串联重复长度多态性（SLRL）和染色质消减（SCL）的诱导作用。在所测试的浓度下，硫酸镍诱导了SLRL，在减数分裂前和减数分裂后阶段活性达到峰值。除了在测试的最高浓度下，它未能产生SCL，在该浓度下，对于汇总数据而言，XO雄性的诱导是显著的。