Horikawa K, Sera N, Tokiwa H, Kada T
Mutat Res. 1986 Jun;174(2):89-92. doi: 10.1016/0165-7992(86)90096-5.
The rec-assay of the nitropyrenes in Bacillus subtilis was performed. All nitropyrene derivatives were positive in this system. Especially, 3 isomers of 1,3-, 1,6- and 1,8-dinitropyrene and 4-nitropyrene were found to possess strong DNA-damaging capacities at extremely low concentrations.
对枯草芽孢杆菌中的硝基芘进行了重组分析。所有硝基芘衍生物在该系统中均呈阳性。特别是,发现1,3 -、1,6 -和1,8 -二硝基芘的3种异构体以及4 -硝基芘在极低浓度下具有很强的DNA损伤能力。