Zhao Jiayi, Han Yiping, Li Jiamei, Chai Rong, Bai Chong
Department of Respiratory and Critical Care Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Department of Psychology, Second Military Medical University, Shanghai 200433, P.R. China.
Oncol Lett. 2019 Mar;17(3):3233-3240. doi: 10.3892/ol.2019.10012. Epub 2019 Feb 4.
The present study explored the association between and . Co-existing mutations were found in 17 patients. and mutations were associated with carbohydrate antigen 19-9 expression, invasive growth, vacuolar signs and margin lobulation on chest CT. The incidence of distant metastasis (bone and adrenal) with and mutations was greater than that of local metastasis (pleura). Patients with the wild-type genes experienced longer progression-free survival (PFS) times than those with .
本研究探讨了[具体内容1]与[具体内容2]之间的关联。在17例患者中发现了共存突变。[具体基因1]和[具体基因2]突变与碳水化合物抗原19-9表达、侵袭性生长、空泡征及胸部CT上的边缘分叶有关。伴有[具体基因1]和[具体基因2]突变的远处转移(骨和肾上腺)发生率高于局部转移(胸膜)。野生型基因患者的无进展生存期(PFS)比[具体基因]突变患者更长。