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抗精神病药所致帕金森综合征中复发性舌震颤

Re-emergent Tongue Tremor in Neuroleptic-induced Parkinsonism.

作者信息

Prasad Shweta, Holla Vikram V, Pal Pramod Kumar

机构信息

Department of Clinical Neurosciences, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore-560029, Karnataka, IN.

Department of Neurology, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore-560029, Karnataka, IN.

出版信息

Tremor Other Hyperkinet Mov (N Y). 2019 Mar 6;9:632. doi: 10.7916/7ndm-gx63. eCollection 2019.

DOI:10.7916/7ndm-gx63
PMID:30867978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6411466/
Abstract

BACKGROUND

A re-emergent tremor is suggested to be specific to Parkinson's disease and although a tongue tremor has been reported in levosulpiride-induced parkinsonism (LIP), re-emergence has never been reported.

CASE REPORT

A 59-year-old female presented with a 3-month history of bradykinesia, 2-week history of right-leg tremor, and 10-day history of lip and tongue tremor. A review of the medication revealed a 15-month history of levosulpiride consumption. On examination, asymmetric bradykinesia, rigidity, rest tremor of the right leg, and re-emergent tongue tremor were observed. The parkinsonism subsided after levosulpiride was stopped.

DISCUSSION

This is the first report of re-emergent tongue tremor in LIP.

摘要

背景

再发性震颤被认为是帕金森病所特有的,尽管已有左旋硫必利诱发帕金森综合征(LIP)时出现舌震颤的报道,但再发性舌震颤从未被报道过。

病例报告

一名59岁女性,有3个月的运动迟缓病史、2周的右腿震颤病史以及10天的唇和舌震颤病史。回顾用药情况发现有15个月的左旋硫必利用药史。检查时,观察到不对称性运动迟缓、肌强直、右腿静止性震颤和再发性舌震颤。停用左旋硫必利后帕金森综合征症状消退。

讨论

这是LIP中再发性舌震颤的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/6411466/85f3b5a4163f/tre-09-632-11942-1-SP-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/6411466/85f3b5a4163f/tre-09-632-11942-1-SP-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/6411466/85f3b5a4163f/tre-09-632-11942-1-SP-g001.jpg

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本文引用的文献

1
Resting and Reemergent Tongue Tremor as Presenting Symptoms of Parkinson's Disease.静止性和再发性舌震颤作为帕金森病的首发症状
Mov Disord Clin Pract. 2016 Aug 3;4(2):273-274. doi: 10.1002/mdc3.12408. eCollection 2017 Mar-Apr.
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Levosulpiride-induced Movement Disorders.左旋舒必利引起的运动障碍。
J Pharmacol Pharmacother. 2017 Oct-Dec;8(4):177-181. doi: 10.4103/jpp.JPP_32_17.
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Resting and re-emergent tongue tremor in Parkinson's disease.帕金森病中的静止性和再发性舌震颤。
BMJ Case Rep. 2017 Nov 1;2017:bcr-2017-221808. doi: 10.1136/bcr-2017-221808.
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Re-emergent tremor in a dystonic SWEDD case.一名肌张力障碍性SWEDD病例中出现的再发性震颤。
Mov Disord. 2012 Mar;27(3):462-3. doi: 10.1002/mds.24040. Epub 2012 Jan 5.
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Levosulpiride-induced movement disorders.左旋舒必利引起的运动障碍。
Mov Disord. 2009 Nov 15;24(15):2249-53. doi: 10.1002/mds.22805.
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Levosulpiride-induced resting orolingual tremor.左旋舒必利诱发的静止性口面部震颤。
Mov Disord. 2009 Aug 15;24(11):1700-1. doi: 10.1002/mds.22578.