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大鼠膝关节内侧副韧带的韧带旁组织:超微结构研究

Epiligament Tissue of the Medial Collateral Ligament in Rat Knee Joint: Ultrastructural Study.

作者信息

Georgiev Georgi P, Iliev Alexandar, Kotov Georgi, Nedialkova Violeta K, Kirkov Vidin, Landzhov Boycho

机构信息

Orthopaedics and Traumatology, Queen Giovanna Hospital, Sofia, BGR.

Pathology, Medical University of Sofia, Sofia, BGR.

出版信息

Cureus. 2019 Jan 2;11(1):e3812. doi: 10.7759/cureus.3812.

DOI:10.7759/cureus.3812
PMID:30868026
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6402729/
Abstract

Introduction Recent studies stressed the importance of the epiligament in ligament nutrition and healing. While ligaments of the knee joint have been the subject of extensive research, the epiligament of the medial collateral ligament has received only limited attention. The aim of our study was to present the ultrastructural morphological features of the epiligament of the medial collateral ligament in a rat knee joint. Materials and methods For the present study, we used eight eight-month-old male Wistar rats. A transmission electron microscopic study of the epiligament was conducted according to standard protocol. Results In the epiligament, we described the presence of fibroblasts with the typical features of protein-synthesizing cells, as well as fibrocytes and adipocytes. We noted an abundance of blood vessels and nerve elements. Collagen fibers were organized in multidirectional bundles. Conclusions Our findings confirm that the cells and structures of the epiligament play an important role in the nutrition and healing of the medial collateral ligament.

摘要

引言 近期研究强调了韧带系膜在韧带营养和愈合中的重要性。虽然膝关节韧带一直是广泛研究的对象,但内侧副韧带的韧带系膜仅受到有限的关注。我们研究的目的是呈现大鼠膝关节内侧副韧带韧带系膜的超微结构形态特征。材料与方法 在本研究中,我们使用了八只八个月大的雄性Wistar大鼠。根据标准方案对韧带系膜进行了透射电子显微镜研究。结果 在韧带系膜中,我们描述了具有蛋白质合成细胞典型特征的成纤维细胞,以及纤维细胞和脂肪细胞的存在。我们注意到有大量的血管和神经成分。胶原纤维呈多方向束状排列。结论 我们的研究结果证实,韧带系膜的细胞和结构在内侧副韧带的营养和愈合中起重要作用。

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本文引用的文献

1
Matrix Metalloproteinase-2 and -9 Expression in the Epiligament of the Medial Collateral and Anterior Cruciate Ligament in Human Knees: A Comparative Study.人膝关节内侧副韧带和前交叉韧带韧带膜中基质金属蛋白酶-2和-9的表达:一项比较研究
Cureus. 2018 Nov 5;10(11):e3550. doi: 10.7759/cureus.3550.
2
Light and electron microscopic study of the medial collateral ligament epiligament tissue in human knees.人膝关节内侧副韧带副韧带组织的光镜和电镜研究
World J Orthop. 2017 May 18;8(5):372-378. doi: 10.5312/wjo.v8.i5.372.
3
Histological and ultrastructural evaluation of the early healing of the lateral collateral ligament epiligament tissue in a rat knee model.
The Epiligament: Structure, Postnatal Development and Role in Ligament Healing.上韧带:结构、出生后发育及在韧带愈合中的作用
Cureus. 2019 Jun 5;11(6):e4836. doi: 10.7759/cureus.4836.
外侧副韧带附丽组织在大鼠膝关节模型中的早期愈合的组织学和超微结构评价。
BMC Musculoskelet Disord. 2010 Jun 13;11:117. doi: 10.1186/1471-2474-11-117.
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Fine vascular anatomy of adult rabbit knee ligaments.成年兔膝关节韧带的精细血管解剖结构。
J Anat. 1990 Oct;172:69-79.
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Intrinsic innervation of the rat knee joint articular capsule and ligaments.大鼠膝关节关节囊和韧带的内在神经支配。
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The "epiligament" of the rabbit medial collateral ligament: a quantitative morphological study.兔内侧副韧带的“韧带外组织”:一项定量形态学研究。
Connect Tissue Res. 1991;27(1):33-50. doi: 10.3109/03008209109006993.