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苯唑西林治疗期间出现严重中性粒细胞减少症并伴有肝炎

Profound Neutropenia with Concomitant Hepatitis During Oxacillin Therapy.

作者信息

Miller John B, Gelber Allan C

机构信息

Rheumatology, Johns Hopkins University School of Medicine, Baltimore, USA.

出版信息

Cureus. 2019 Jan 3;11(1):e3823. doi: 10.7759/cureus.3823.

Abstract

Beta-lactam antibiotics are widely used and generally well-tolerated. Neutropenia and hepatitis are two adverse drug reactions associated with beta-lactam therapy that are typically benign and reversible, yet have seldom been reported as simultaneous occurrences. This narrative describes these adverse drug reactions during oxacillin therapy.

摘要

β-内酰胺类抗生素广泛应用,且一般耐受性良好。中性粒细胞减少症和肝炎是与β-内酰胺治疗相关的两种药物不良反应,通常为良性且可逆,但很少有同时发生的报道。本文叙述了苯唑西林治疗期间的这些药物不良反应。

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