Department of Pediatrics, Division of Pediatric Cardiology, Columbia University Medical Center, Morgan Stanley Children's Hospital of NewYork-Presbyterian, New York, New York.
Birth Defects Res. 2019 May 1;111(8):389-394. doi: 10.1002/bdr2.1478. Epub 2019 Mar 14.
Advances in fetal echocardiography have allowed for the prenatal diagnosis of congenital heart disease and an understanding of its natural history in utero. This insight has led to the development of fetal cardiac intervention (FCI) for select defects to prevent significant morbidity or mortality postnatally. Fetal aortic valvuloplasty (FAV) may be performed to prevent progression to hypoplastic left heart syndrome, a severe form of congenital heart disease, in utero. The current review focuses on this type of FCI and discusses the history of FAV, the rationale for intervention, candidate selection, procedural technique, and outcomes to date. Finally, the importance of building a multidisciplinary team to perform FCI is addressed.
胎儿超声心动图的进步使得先天性心脏病的产前诊断成为可能，并能够了解其在子宫内的自然病史。这一认识导致了选择性缺陷的胎儿心脏介入（FCI）的发展，以防止出生后出现严重的发病率或死亡率。胎儿主动脉瓣成形术（FAV）可用于预防宫内发生左心发育不良综合征，这是一种严重的先天性心脏病。目前的综述重点关注这种类型的 FCI，并讨论 FAV 的历史、干预的基本原理、候选者选择、手术技术以及迄今为止的结果。最后，讨论了建立一个多学科团队来进行 FCI 的重要性。
