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氰基丙烯酸酯粘合剂在猫角膜腐骨手术治疗中的应用:16例(2011 - 2018年)

Use of cyanoacrylate adhesive in the surgical management of feline corneal sequestrum: 16 cases (2011-2018).

作者信息

Pumphrey Stephanie A, Desai Sujata J, Pizzirani Stefano

机构信息

Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts.

出版信息

Vet Ophthalmol. 2019 Nov;22(6):859-863. doi: 10.1111/vop.12663. Epub 2019 Mar 14.

Abstract

OBJECTIVE

To evaluate the use of cyanoacrylate adhesive as an adjunct to lamellar keratectomy in cats with corneal sequestrum.

METHODS

Medical records were reviewed to identify cats with naturally occurring midstromal corneal sequestra treated with lamellar keratectomy and cyanoacrylate adhesive. All cats also had a bandage contact lens placed for postoperative comfort. Data collected included breed, age, sex, and reproductive status of the cat, eye involved, presence or absence of neovascularization at the time of surgery, history of prior sequestra, additional ocular procedures performed, use of neuromuscular blocking agents, procedure time, time to cessation of topical medications, time to recurrence or last follow-up, and complications aside from recurrence.

RESULTS

Sixteen cats met study criteria, with a median follow-up time of 17.5 months in those without recurrence. Median time to cessation of topical medications was 4 weeks. Fourteen cats (87%) have not experienced recurrence. Other than recurrence in two cats, no significant complications were noted. Aside from purebred status, no commonalities were found between the two cats with recurrence. Neuromuscular blocking agents were not used during surgery in most cases. Median procedure time was 10 minutes.

CONCLUSIONS

Cyanoacrylate adhesive is an effective and safe alternative to grafting procedures in cats undergoing lamellar keratectomy for treatment of corneal sequestrum. Recurrence rates are comparable to those seen with grafting techniques. Benefits of this approach include decreased anesthesia time, lower procedure costs, and short duration of postoperative treatment.

摘要

目的

评估氰基丙烯酸酯粘合剂作为辅助手段在患有角膜腐骨的猫行板层角膜切除术时的应用。

方法

回顾医疗记录,以确定接受板层角膜切除术和氰基丙烯酸酯粘合剂治疗的患有自然发生的基质中层角膜腐骨的猫。所有猫术后均佩戴绷带式隐形眼镜以提高舒适度。收集的数据包括猫的品种、年龄、性别和生殖状况、患眼、手术时有无新生血管、既往腐骨病史、是否进行其他眼科手术、是否使用神经肌肉阻滞剂、手术时间、局部用药停止时间、复发时间或最后随访时间以及除复发外的并发症。

结果

16只猫符合研究标准,未复发的猫中位随访时间为17.5个月。局部用药停止的中位时间为4周。14只猫(87%)未复发。除两只猫复发外,未发现明显并发症。除了纯种身份外,两只复发的猫之间没有发现共同特征。大多数病例手术期间未使用神经肌肉阻滞剂。中位手术时间为10分钟。

结论

对于接受板层角膜切除术治疗角膜腐骨的猫,氰基丙烯酸酯粘合剂是一种有效且安全的替代移植手术的方法。复发率与移植技术相当。这种方法的优点包括减少麻醉时间、降低手术成本和缩短术后治疗时间。

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