Mastro-Martínez Ignacio, Pérez-Ortega María J, Urrutia Emilia, Ortega-Acosta María J, Pacheco Sánchez-Lafuente Francisco J
Unidad de Gestión Clínica de Pediatría, Baza, España.
Hospital Universitario Virgen de las Nieves, Servicio de Pediatría y Oncohematología Pediátricas, Granada, España.
Arch Argent Pediatr. 2019 Apr 1;117(2):e163-e166. doi: 10.5546/aap.2019.e163.
Congenital neuroblastoma is the most frequent malignant solid tumor in the neonatal period. The clinical presentation is usually either by prenatal diagnosis or by palpation of an abdominal mass. Staging allows classifying it according to risk groups with a different prognosis and treatment. In the neonatal period, it is characterized by a high rate of spontaneous regression and good prognosis (disease-free survival at 5 years greater than 90 %). We present a clinical case of congenital neuroblastoma whose presentation, shock and hypertension, was only described on a previous occasion. Antihypertensive treatment along with systemic chemotherapy produced clinical control and patient improvement.
先天性神经母细胞瘤是新生儿期最常见的恶性实体瘤。临床表现通常为产前诊断或通过触诊腹部肿块发现。分期有助于根据预后和治疗不同的风险组对其进行分类。在新生儿期，其特点是自发消退率高且预后良好（5年无病生存率大于90%）。我们报告一例先天性神经母细胞瘤的临床病例，其表现为休克和高血压，此前仅有过相关描述。抗高血压治疗联合全身化疗实现了临床控制并使患者病情好转。
