Department of Plastic, Reconstructive, and Aesthetic Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Aesthet Surg J. 2019 Mar 14;39(Suppl_2):S67-S72. doi: 10.1093/asj/sjz036.
Surgeons must select the optimal suture materials for tissue approximation to maximize wound healing and scar aesthetics. Thus, knowledge regarding their characteristics is crucial to minimize ischaemia, excess wound tension, and tissue injury. This article describes the selection of various suture materials available today and their intended design. Modern suture material should have predictable tensile strength, good handling, secure knot-tying properties, and could be enhanced with an antibacterial agent to resist infection. Tensile strength is limited by suture size. The smallest suture size that will accomplish the purpose should be chosen to minimize tissue trauma and foreign material within tissues. Monofilament suture has lower resistance when passed through tissues, whereas multifilament sutures possesses higher tensile strength and flexibility but greater tissue friction and pose risks of suture sinus and infection. Natural absorbable sutures derived from mammalian collagen undergo enzymatic degradation whereas synthetic polymers undergo hydrolysis. Collagen or polymer structures in the suture can be modified to control absorption time. In contrast, nonabsorbable sutures typically cause an inflammatory reaction that eventually encapsulates by fibrous tissue formation. Excess reaction leads to chronic inflammation, suboptimal scarring, or suture extrusion. More recently, barbed sutures have transformed the way surgeons approximate wounds by eliminating knots, distributing wound tension, and increasing efficiency of closure. Similarly, modern skin adhesives function both as wound closure devices as well as an occlusive dressing. They eliminate the need for skin sutures, thus improving scar aesthetics while sealing the wound from the external environment.
外科医生必须选择最佳的缝合材料来进行组织吻合,以最大限度地促进伤口愈合和改善疤痕美观。因此,了解缝合材料的特性对于最小化缺血、过度伤口张力和组织损伤至关重要。本文描述了当今可用的各种缝合材料的选择及其设计用途。现代缝合材料应具有可预测的拉伸强度、良好的操作性能、可靠的打结性能,并且可以添加抗菌剂以抵抗感染。拉伸强度受缝线尺寸限制。应选择能够达到目的的最小缝线尺寸,以最大程度地减少组织创伤和组织内的异物。单丝缝线在穿过组织时的阻力较小,而多丝缝线具有更高的拉伸强度和柔韧性,但组织摩擦更大,并且存在缝合窦和感染的风险。源自哺乳动物胶原蛋白的天然可吸收缝线会发生酶降解,而合成聚合物则会发生水解。缝线中的胶原或聚合物结构可以进行修饰以控制吸收时间。相比之下,不可吸收缝线通常会引起炎症反应,最终被纤维组织包裹。过度的反应会导致慢性炎症、疤痕不佳或缝线挤出。最近,带倒刺的缝线通过消除结、分布伤口张力和提高闭合效率,改变了外科医生处理伤口的方式。同样,现代皮肤粘合剂既可以作为伤口闭合装置,也可以作为封闭敷料。它们消除了对皮肤缝线的需求,从而改善了疤痕美观度,同时将伤口与外部环境密封。