Suppr超能文献

强化封闭式切口负压疗法治疗感染性瘢痕

Enhanced Closed Incisional Negative Pressure Therapy for Treating Infectious Scars.

作者信息

Liu Xingran, Ji Qiumei, Yang Jing, Li Qingfeng, Liu Kai, Huang Ru-Lin

机构信息

From the Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Shanghai Institute for Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Plast Reconstr Surg Glob Open. 2025 May 15;13(5):e6776. doi: 10.1097/GOX.0000000000006776. eCollection 2025 May.

Abstract

BACKGROUND

Chronic infectious pathological scars, characterized by mutual reinforcement between infection and pathological scarring, pose challenges in reconstructive surgery. We introduce an enhanced closed incisional negative pressure therapy following a 1-stage surgery to simultaneously eradicate infection and alleviate wound tension.

METHODS

A total of 25 patients who underwent chronic infectious pathological scar treatment by using this enhanced closed incisional negative pressure therapy were retrospectively reviewed. The outcomes were evaluated by postoperative recurrence frequency of infection and scarring during a 1-year follow-up, as well as the Patient and Observer Scar Assessment Scale and quality-of-life scores.

RESULTS

After treatment, no serious complications, such as incision dehiscence, occurred. The average wound healing time was 12.68 days. Only 1 patient experienced surgical site scarring. Besides, average infection frequency decreased significantly from 6.40 to 0.00 times per year ( < 0.0001). The Patient and Observer Scar Assessment Scale score decreased from 81.60 to 25.36 ( < 0.0001), whereas the quality-of-life score increased from 2.20 to 4.88 ( < 0.0001).

CONCLUSIONS

The enhanced closed incisional negative pressure therapy effectively facilitated infectious wound healing in a 1-stage operation and simultaneously prevented infection and scarring recurrence in long-term follow-up, resulting in satisfactory postoperative outcomes.

摘要

背景

慢性感染性病理性瘢痕以感染与病理性瘢痕形成相互促进为特征,给重建手术带来挑战。我们在一期手术后引入强化的闭合切口负压治疗,以同时根除感染并减轻伤口张力。

方法

回顾性分析了25例行强化闭合切口负压治疗慢性感染性病理性瘢痕的患者。通过术后1年随访期间感染和瘢痕形成的复发频率、患者和观察者瘢痕评估量表以及生活质量评分来评估治疗效果。

结果

治疗后未发生切口裂开等严重并发症。平均伤口愈合时间为12.68天。仅1例患者出现手术部位瘢痕形成。此外,平均每年感染次数从6.40次显著降至0.00次(<0.0001)。患者和观察者瘢痕评估量表评分从81.60降至25.36(<0.0001),而生活质量评分从2.20升至4.88(<0.0001)。

结论

强化的闭合切口负压治疗在一期手术中有效促进了感染性伤口愈合,同时在长期随访中预防了感染和瘢痕形成的复发,术后效果满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4c4/12080673/7b91cc4607c5/gox-13-e6776-g001.jpg

相似文献

1
Enhanced Closed Incisional Negative Pressure Therapy for Treating Infectious Scars.
Plast Reconstr Surg Glob Open. 2025 May 15;13(5):e6776. doi: 10.1097/GOX.0000000000006776. eCollection 2025 May.
4
The impact of closed incisional negative pressure therapy on anterior lateral thigh flap donor site healing and scarring: A retrospective case-control study.
J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):152-159. doi: 10.1016/j.bjps.2021.05.049. Epub 2021 Jun 13.
7
[Effects of scar excision combined with negative-pressure on repair of hypertrophic scar in burn children].
Zhonghua Shao Shang Za Zhi. 2017 Jul 20;33(7):410-414. doi: 10.3760/cma.j.issn.1009-2587.2017.07.003.
8
A systematic review evaluating the influence of incisional Negative Pressure Wound Therapy on scarring.
Wound Repair Regen. 2021 Jan;29(1):8-19. doi: 10.1111/wrr.12858. Epub 2020 Aug 21.
10
Use of Negative Pressure Wound Therapy on Closed Surgical Incision After Total Ankle Arthroplasty.
Foot Ankle Int. 2015 Jul;36(7):787-94. doi: 10.1177/1071100715574934. Epub 2015 Mar 3.

本文引用的文献

1
5
A Review of Barbed Sutures-Evolution, Applications and Clinical Significance.
Bioengineering (Basel). 2023 Mar 27;10(4):419. doi: 10.3390/bioengineering10040419.
6
The application of corticosteroids for pathological scar prevention and treatment: current review and update.
Burns Trauma. 2023 Mar 18;11:tkad009. doi: 10.1093/burnst/tkad009. eCollection 2023.
7
Laser Combined with Radiotherapy for Keloid Treatment: A Novel and Efficient Comprehensive Therapy with a Lower Recurrence Rate.
Plast Reconstr Surg. 2023 Dec 1;152(6):1022e-1029e. doi: 10.1097/PRS.0000000000010376. Epub 2023 Mar 8.
8
Global research status of pathological scar reported over the period 2001-2021: A 20-year bibliometric analysis.
Int Wound J. 2023 May;20(5):1725-1738. doi: 10.1111/iwj.13988. Epub 2022 Oct 23.
9
Skin biomechanics: a potential therapeutic intervention target to reduce scarring.
Burns Trauma. 2022 Aug 23;10:tkac036. doi: 10.1093/burnst/tkac036. eCollection 2022.
10
Island Perforator Muscle Flaps for Chronic Osteomyelitis of the Lower Extremities: A Retrospective Analysis of 21 Consecutive Cases.
Plast Reconstr Surg. 2022 Sep 1;150(3):677-687. doi: 10.1097/PRS.0000000000009472. Epub 2022 Jul 6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验