Liu Xingran, Ji Qiumei, Yang Jing, Li Qingfeng, Liu Kai, Huang Ru-Lin
From the Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Institute for Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Plast Reconstr Surg Glob Open. 2025 May 15;13(5):e6776. doi: 10.1097/GOX.0000000000006776. eCollection 2025 May.
Chronic infectious pathological scars, characterized by mutual reinforcement between infection and pathological scarring, pose challenges in reconstructive surgery. We introduce an enhanced closed incisional negative pressure therapy following a 1-stage surgery to simultaneously eradicate infection and alleviate wound tension.
A total of 25 patients who underwent chronic infectious pathological scar treatment by using this enhanced closed incisional negative pressure therapy were retrospectively reviewed. The outcomes were evaluated by postoperative recurrence frequency of infection and scarring during a 1-year follow-up, as well as the Patient and Observer Scar Assessment Scale and quality-of-life scores.
After treatment, no serious complications, such as incision dehiscence, occurred. The average wound healing time was 12.68 days. Only 1 patient experienced surgical site scarring. Besides, average infection frequency decreased significantly from 6.40 to 0.00 times per year ( < 0.0001). The Patient and Observer Scar Assessment Scale score decreased from 81.60 to 25.36 ( < 0.0001), whereas the quality-of-life score increased from 2.20 to 4.88 ( < 0.0001).
The enhanced closed incisional negative pressure therapy effectively facilitated infectious wound healing in a 1-stage operation and simultaneously prevented infection and scarring recurrence in long-term follow-up, resulting in satisfactory postoperative outcomes.
慢性感染性病理性瘢痕以感染与病理性瘢痕形成相互促进为特征,给重建手术带来挑战。我们在一期手术后引入强化的闭合切口负压治疗,以同时根除感染并减轻伤口张力。
回顾性分析了25例行强化闭合切口负压治疗慢性感染性病理性瘢痕的患者。通过术后1年随访期间感染和瘢痕形成的复发频率、患者和观察者瘢痕评估量表以及生活质量评分来评估治疗效果。
治疗后未发生切口裂开等严重并发症。平均伤口愈合时间为12.68天。仅1例患者出现手术部位瘢痕形成。此外,平均每年感染次数从6.40次显著降至0.00次(<0.0001)。患者和观察者瘢痕评估量表评分从81.60降至25.36(<0.0001),而生活质量评分从2.20升至4.88(<0.0001)。
强化的闭合切口负压治疗在一期手术中有效促进了感染性伤口愈合,同时在长期随访中预防了感染和瘢痕形成的复发,术后效果满意。