Pöyhönen Leena, Kivekäs Ilkka, Silvola Juha, Poe Dennis, Rautiainen Markus
a Department of Otorhinolaryngology, University of Tampere, Faculty of Medicine and Life Sciences, Tampere University Hospital , Tampere , Finland.
b Department of Otorhinolaryngology, Akershus Universitetssykehus HF , Lorenskog , Norway.
Acta Otolaryngol. 2019 Mar;139(3):238-242. doi: 10.1080/00016489.2018.1562218. Epub 2019 Mar 14.
Most of the tests to evaluate the eustachian tube (ET) function are focused on the ventilation function of the ET.
Here we evaluate mucociliary function of the ET in patients with ET dysfunction.
Ten patients with ET dysfunction were enrolled into the study. Six patients had chronic tympanic membrane retraction and four patients had chronic middle ear effusion (MEE). All patients had intact tympanic membranes. Tympanometry and clinical examinations were done to all patients. Mucociliary function was evaluated with technetium labeled albumin and blue dye. Tympanometry and clinical examinations were done to six patients with chronic tympanic membrane retraction and four patients with chronic middle ear effusion (MEE). Mucociliary function of the ET was evaluated with technetium labeled albumin and blue dye placed into middle ear through an intact tympanic membrane and followed from nasopharynx ET orifice (blue dye) and with gamma camera (technetium).
Blue dye was observed in tubal orifice in six (6 of 10) patients during 30 min observation. Five of those patients (5 of 6) had tympanic membrane retraction and one patient (1 of 6) had MEE. Tracer activity decreased from middle ear in six (6 of 10) patients. Four of those patients had tympanic membrane retraction and two had MEE.
Mucociliary function of the ET seems to be better in patients with tympanic membrane retraction than patients with middle ear effusion.
Mucociliary function of the ET is an important function for middle ear aeration, blue dye test is easily available to be used also in clinical practice.
大多数评估咽鼓管（ET）功能的测试都集中在ET的通气功能上。
在此我们评估ET功能障碍患者的ET黏液纤毛功能。
10例ET功能障碍患者纳入本研究。6例患者有慢性鼓膜内陷，4例患者有慢性中耳积液（MEE）。所有患者鼓膜均完整。对所有患者进行了鼓室图检查和临床检查。用锝标记白蛋白和蓝色染料评估黏液纤毛功能。对6例慢性鼓膜内陷患者和4例慢性中耳积液（MEE）患者进行了鼓室图检查和临床检查。通过完整鼓膜将锝标记白蛋白和蓝色染料注入中耳，然后从鼻咽部ET开口处（蓝色染料）以及用γ相机（锝）追踪，评估ET的黏液纤毛功能。
在30分钟观察期间，10例患者中有6例（6/10）在咽鼓管开口处观察到蓝色染料。其中5例患者（5/6）有鼓膜内陷，1例患者（1/6）有中耳积液。10例患者中有6例（6/10）示踪剂活性从中耳下降。其中4例患者有鼓膜内陷，2例有中耳积液。
鼓膜内陷患者的ET黏液纤毛功能似乎比中耳积液患者更好。
ET的黏液纤毛功能是中耳通气的一项重要功能，蓝色染料试验在临床实践中也易于使用。
