Ho Portia, Bulsara Max, Downs Jenny, Patman Shane, Bulsara Caroline, Hill Anne-Marie
School of Physiotherapy, the University of Notre Dame Australia, Fremantle, Australia.
The Western Australian Group for Evidence Informed Healthcare Practice: a Joanna Briggs Institute Centre of Excellence.
JBI Database System Rev Implement Rep. 2019 Mar;17(3):390-413. doi: 10.11124/JBISRIR-2017-003798.
The objective of the review was too synthesize the best available evidence on the incidence and prevalence of falls among adults with intellectual disability (ID).
Falls among adults with ID frequently cause physical injury and may negatively impact on their quality of life. Studies investigating falls among people with ID have used differing methods and populations, making it difficult to determine the scope and extent of this problem.
This review considered all studies that included adults with ID aged 18 years and over and which reported percentage/numbers of individuals who fell, and the total number of falls and injurious falls sustained from a fall. Studies were included if they were conducted within community or residential settings. Studies that were conducted in hospitals were excluded. Cohort studies, case-control and cross-sectional studies were included. Studies that used an experimental design, both randomized controlled and quasi experimental design, were also included.
A three-step search strategy was undertaken for published and unpublished literature in English from 1990 to 2017. An initial search of MEDLINE and CINAHL was undertaken before a more extensive search was conducted using keywords and index terms across 11 electronic databases. Two independent reviewers assessed the methodological quality of the included studies using the Joanna Briggs Institute standardized critical appraisal instrument for prevalence studies (Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data).Data was extracted using the Joanna Briggs Institute's standardized extraction tool. Data that directly reported or could be used to calculate the incidence and prevalence of falls were extracted. Quantitative data for the number (proportion) of people who fell were pooled in statistical meta-analysis using STATA version 14 (Stata Corp LLC, Texas, USA). Data measuring incidence of falls (rate of falls for the duration of the study) and incidence of injurious falls (rate of falls resulting in one or more injuries for the duration of the study) could not be pooled in meta-analysis, hence results have been presented in a narrative form including tables. Standard GRADE (Grading of Recommendations Assessment, Development and Evaluation) evidence assessment of outcomes is also reported.
Nine studies were eligible for inclusion in this review. Eight articles were observational cohort studies which reported on the incidence/prevalence of falls as outcome measures, and one article was a quasi-experimental study design. Overall the methodological quality of the included studies was considered moderate. The pooled proportion of people with ID who fell (four studies, 854 participants) was 39% (95% CI [0.35%-0.43%], very low GRADE evidence). The rate of falls (eight studies, 782 participants) ranged from 0.54 to 6.29 per person year (very low GRADE evidence). The rate of injurious falls (two studies, 352 participants) ranged from 0.33 to 0.68 per person year (very low GRADE evidence).
Synthesized findings demonstrate that people with ID, who live in community or residential settings, may fall more frequently, and at a younger age, compared to general community populations. Studies should take a consistent approach to measuring and reporting falls outcomes. Further research is recommended to identify the impact of falls on health related outcomes for people with ID and subsequently evaluate falls interventions for their efficacy.
本综述的目的是综合关于成年智力残疾(ID)者跌倒发生率和患病率的最佳现有证据。
成年ID者跌倒经常导致身体损伤,并可能对他们的生活质量产生负面影响。调查ID者跌倒情况的研究采用了不同的方法和人群,这使得难以确定该问题的范围和程度。
本综述纳入所有包含18岁及以上成年ID者的研究,这些研究报告了跌倒个体的百分比/数量、跌倒总数以及跌倒导致的受伤跌倒数量。如果研究是在社区或居住环境中进行的,则予以纳入。排除在医院进行的研究。纳入队列研究、病例对照研究和横断面研究。使用实验设计的研究,包括随机对照和准实验设计,也予以纳入。
对1990年至2017年以英文发表和未发表的文献采用三步搜索策略。在使用11个电子数据库中的关键词和索引词进行更广泛搜索之前,先对MEDLINE和CINAHL进行初步搜索。两名独立评审员使用乔安娜·布里格斯研究所针对患病率研究的标准化批判性评价工具(乔安娜·布里格斯研究所报告患病率数据研究的批判性评价清单)评估纳入研究的方法学质量。使用乔安娜·布里格斯研究所的标准化提取工具提取数据。提取直接报告或可用于计算跌倒发生率和患病率的数据。使用STATA 14版(美国德克萨斯州Stata公司有限责任公司)对跌倒人数(比例)的定量数据进行统计荟萃分析。无法在荟萃分析中汇总测量跌倒发生率(研究期间的跌倒率)和受伤跌倒发生率(研究期间导致一次或多次受伤的跌倒率)的数据,因此结果以叙述形式呈现,包括表格。还报告了结果的标准GRADE(推荐分级评估、制定和评价)证据评估。
九项研究符合本综述的纳入标准。八篇文章是观察性队列研究,报告了跌倒的发生率/患病率作为结局指标,一篇文章是准实验研究设计。总体而言,纳入研究的方法学质量被认为中等。ID者跌倒的合并比例(四项研究,854名参与者)为39%(95%可信区间[0.35%-0.43%],极低GRADE证据)。跌倒率(八项研究,782名参与者)每人每年范围为0.54至6.29(极低GRADE证据)。受伤跌倒率(两项研究,352名参与者)每人每年范围为0.33至0.68(极低GRADE证据)。
综合研究结果表明,与一般社区人群相比,生活在社区或居住环境中的ID者可能跌倒更频繁,且年龄更小。研究应采用一致的方法来测量和报告跌倒结局。建议进一步研究以确定跌倒对ID者健康相关结局的影响,并随后评估跌倒干预措施的效果。