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危重症成年患者跌倒的发生率及相关危险因素:一项观察性研究

Incidence and Associated Risk Factors for Falls in Adults Following Critical Illness: An Observational Study.

作者信息

Parry Selina M, Morris Peter E, Larkin Jane, Beach Lisa J, Mayer Kirby P, Oliveira Cristino C, McGinley Jennifer, Puthucheary Zudin A, Koye Digsu N, Lamb Karen E, Denehy Linda, Granger Catherine L

机构信息

Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.

Department of Physiotherapy, The Royal Melbourne Hospital, Parkville, VIC, Australia.

出版信息

Crit Care Med. 2025 Jun 1;53(6):e1257-e1268. doi: 10.1097/CCM.0000000000006668. Epub 2025 Apr 18.

Abstract

OBJECTIVE

To explore the incidence of falls and associated risk factors in the first year after hospital discharge in survivors of critical illness.

DESIGN

Prospective single-site observational study.

SETTING

University-affiliated mixed ICU.

PATIENTS

One hundred ICU adults who required invasive ventilation for 48 hours and in an ICU for at least 4 days.

INTERVENTIONS

Not applicable.

MEASUREMENTS AND MAIN RESULTS

Falls were monitored prospectively for 1 year with completion of monthly falls calendars. Falls data included the number of people who had falls/no falls/recurrent falls, falls rate per person per year, and time to first fall. Fall severity was classified according to the Schwenck classification scheme to examine injurious falls requiring medical intervention. Other outcomes considered included assessments of balance, strength, function, cognition, psychologic health, and health-related quality of life. One hundred participants (31% female) were recruited with a mean age of 58.3 ± 16.2 years, and a median ventilation duration of 6.3 days [4.0-9.1]. Sixty-one percent fell at least once in the first year with the majority sustaining two or more falls (81.4%) and one in four sustained an injurious fall requiring medical attention. The falls incidence rate was 4.4 falls per person-year (95% CI, 3.2-5.9), with the highest incidence occurring less than 3 months after hospital discharge (5.9 falls/person-year [95% CI, 4.4-7.8]). Time to first fall or injurious fall was 36 [11-66] and 95 (95% CI, 40-155) days, respectively. Key risk factors for falls at the time of hospital discharge include comorbidities, higher discharge medications, balance, and muscle strength.

CONCLUSIONS

There was a high falls incidence in ICU survivors. The study findings suggest a critical window may exist within the first 3 months after hospital discharge and the need for screening, pharmacological optimization, and exercise training in this patient group.

摘要

目的

探究危重症幸存者出院后第一年的跌倒发生率及相关危险因素。

设计

前瞻性单中心观察性研究。

地点

大学附属医院综合性重症监护病房。

患者

100名成年重症监护病房患者,需有创通气48小时且在重症监护病房至少待4天。

干预措施

不适用。

测量指标及主要结果

通过每月填写跌倒日历对跌倒情况进行前瞻性监测1年。跌倒数据包括跌倒/未跌倒/反复跌倒的人数、每人每年的跌倒发生率以及首次跌倒时间。根据施温克分类方案对跌倒严重程度进行分类,以检查需要医疗干预的伤害性跌倒情况。还考虑了其他结果,包括平衡、力量、功能、认知、心理健康及健康相关生活质量的评估。招募了100名参与者(31%为女性),平均年龄58.3±16.2岁,中位通气时间为6.3天[4.0 - 9.1]。61%的患者在第一年至少跌倒一次,大多数患者跌倒两次或更多次(81.4%),四分之一的患者发生了需要医疗关注的伤害性跌倒。跌倒发生率为每人每年4.4次(95%置信区间,3.2 - 5.9),最高发生率出现在出院后不到3个月(5.9次/人年[95%置信区间,4.4 - 7.8])。首次跌倒或伤害性跌倒的时间分别为36[11 - 66]天和95天(95%置信区间,40 - 155)。出院时跌倒的关键危险因素包括合并症、出院时用药较多、平衡能力和肌肉力量。

结论

重症监护病房幸存者的跌倒发生率较高。研究结果表明,出院后前3个月可能存在关键窗口期,且该患者群体需要进行筛查、药物优化和运动训练。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/191a/12124207/9b8516c79313/ccm-53-e1257-g001.jpg

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