Gabra G S, Black M, Mitchell R
Vox Sang. 1986;50(3):137-40. doi: 10.1111/j.1423-0410.1986.tb04865.x.
A selected group of women previously immunized in pregnancy by the Rh(D) antigen were boosted with 0.5 ml of Rh(D)-positive frozen recovered red cells from an accredited donor panel. The response was prompt and sustained and increased the anti-D content by almost 10-fold. In spite of the reduced rate of clinical immunisation to the Rh(D) antigen, it was possible to recruit females with anti-D, acquired in pregnancy, for secondary boosting and a programme is recommended which maximizes efficiency and safety.
一组先前在孕期通过Rh(D)抗原进行免疫的女性，用0.5毫升来自认可供体库的Rh(D)阳性冷冻回收红细胞进行加强免疫。反应迅速且持续，抗-D含量增加了近10倍。尽管对Rh(D)抗原的临床免疫发生率有所降低，但仍有可能招募孕期获得抗-D的女性进行二次加强免疫，建议制定一个能使效率和安全性最大化的方案。
