Department of Developmental and Preventive Sciences, Faculty of Dentistry, Kuwait University, Kuwait, Kuwait,
Department of Developmental and Preventive Sciences, Faculty of Dentistry, Kuwait University, Kuwait, Kuwait.
Med Princ Pract. 2019;28(4):341-346. doi: 10.1159/000499594. Epub 2019 Mar 15.
To investigate the oral health status and dental manifestations of children with a history of chronic liver disease (CLD) compared to healthy children.
Twenty children (15 boys and 5 girls) with a history of CLD were compared to 20 healthy controls matched for age and gender. The clinical examination was carried out by the same dentist. Caries prevalence, using the decayed, missing, and filled primary and permanent teeth indices (dmft/DMFT), was recorded. Developmental enamel defects, plaque scores, and gingival overgrowth were also investigated.
No statistically significant differences were found in mean dmft scores for children with a history of CLD (4.9 ± 5.4) and for healthy individuals (3.9 ± 4.5). However, the mean DMFT score was significantly higher (p =0.025) in children with CLD (4.2 ± 4.6) compared to controls (1.7 ± 1.6). The mean decayed teeth parameter (DT) was also significantly higher in children with CLD (p =0.004). All patients with CLD exhibited enamel defects compared to only 33% in the control group (p< 0.05). A higher mean plaque index was observed in children with a history of CLD (p< 0.001). Also, a positive correlation for gingival overgrowth was noted in patients with a history of CLD (p< 0.05). Green staining was evident only in the permanent dentition of 1 child with CLD.
Children with a history of CLD exhibited a high caries prevalence, high plaque scores, and more enamel defects compared to healthy subjects. Gingival overgrowth is less prevalent among pediatric liver transplant patients on tacrolimus therapy.
研究与健康儿童相比，患有慢性肝病（CLD）的儿童的口腔健康状况和牙齿表现。
将 20 名（15 名男孩和 5 名女孩）患有 CLD 病史的儿童与年龄和性别相匹配的 20 名健康对照组进行比较。由同一名牙医进行临床检查。记录龋齿流行率，使用龋失补牙数（dmft/DMFT）指数。还调查了发育性牙釉质缺陷、菌斑评分和牙龈增生。
患有 CLD 病史的儿童的平均 dmft 评分（4.9 ± 5.4）与健康个体（3.9 ± 4.5）之间没有统计学上的显著差异。然而，CLD 儿童的平均 DMFT 评分明显更高（p =0.025）（4.2 ± 4.6）与对照组（1.7 ± 1.6）。CLD 儿童的平均龋齿参数（DT）也明显更高（p =0.004）。与对照组相比，所有患有 CLD 的患者均出现牙釉质缺陷（p<0.05）。患有 CLD 的儿童的平均菌斑指数明显更高（p<0.001）。此外，还注意到 CLD 患者的牙龈增生呈正相关（p<0.05）。只有 1 名患有 CLD 的儿童的恒牙有绿色染色。
与健康儿童相比，患有 CLD 的儿童的龋齿流行率高、菌斑评分高、牙釉质缺陷更多。在接受他克莫司治疗的小儿肝移植患者中，牙龈增生的发生率较低。
