Gayo L, Bonet B, Herranz A S, Iglesias R, Toro M J, Montoya E
Acta Endocrinol (Copenh). 1986 May;112(1):7-11. doi: 10.1530/acta.0.1120007.
The postnatal development of immunoreactive TRH in the central nervous system (CNS), serum TSH and thyroid hormones was studied in both male and female normal rats. While in most structures of the CNS, TRH increased until day 20-30, serum TSH values peaked at day 15 as did T4. Significant differences were also obtained between both sexes in these parameters. These data further support the fact that pituitary-thyroid axis maturation is independent of brain TRH.
对正常雄性和雌性大鼠中枢神经系统（CNS）中免疫反应性促甲状腺激素释放激素（TRH）、血清促甲状腺激素（TSH）和甲状腺激素的产后发育进行了研究。在中枢神经系统的大多数结构中，TRH在第20至30天之前增加，血清TSH值在第15天达到峰值，T4也是如此。在这些参数上两性之间也存在显著差异。这些数据进一步支持了垂体-甲状腺轴成熟独立于脑TRH这一事实。
