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1例应用超短效β受体阻滞剂盐酸兰地洛尔治疗伴有左心室流出道梗阻的应激性心肌病。

A case of ultrashort-acting beta-blocker landiolol hydrochloride for takotsubo syndrome with left ventricular outflow tract obstruction.

作者信息

Takama Takuro, Fukue Mitsunori, Sato Hiroyuki, Taniuchi Masato

机构信息

Department of Cardiology Yamachika Memorial Hospital Odawara Japan.

Department of Emergency and Critical Care Medicine The Jikei University School of Medicine Tokyo Japan.

出版信息

J Gen Fam Med. 2018 Dec 7;20(2):65-67. doi: 10.1002/jgf2.223. eCollection 2019 Mar.

DOI:10.1002/jgf2.223
PMID:30873307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6399582/
Abstract

Takotsubo syndrome (TTS) has been known to have a favorable prognosis. Beta-blockers are reported to be effective for TTS patients with cardiogenic heart failure due to left ventricular outflow tract (LVOT) obstruction. However, there is no report on ultrashort-acting beta-blockers being used for treating TTS, and there are no clear guidelines for their dosages or applications. Herein, we describe a 72-year-old woman in whom landiolol hydrochloride was used in the acute phase of TTS with LVOT obstruction. In this case, the dose of landiolol hydrochloride was increased to 10 μg/kg/min, resulting in improvement of LVOT obstruction, which led to hemodynamic stabilization.

摘要

已知应激性心肌病(TTS)预后良好。据报道,β受体阻滞剂对因左心室流出道(LVOT)梗阻导致的心源性心力衰竭的TTS患者有效。然而,尚无关于使用超短效β受体阻滞剂治疗TTS的报道,其剂量或应用也没有明确的指南。在此,我们描述一名72岁女性,在TTS合并LVOT梗阻的急性期使用了盐酸兰地洛尔。在该病例中,盐酸兰地洛尔的剂量增加至10μg/kg/min,导致LVOT梗阻改善,从而实现血流动力学稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45f/6399582/6794fc81a9b5/JGF2-20-65-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45f/6399582/b3b89fd93b6d/JGF2-20-65-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45f/6399582/6794fc81a9b5/JGF2-20-65-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45f/6399582/b3b89fd93b6d/JGF2-20-65-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45f/6399582/6794fc81a9b5/JGF2-20-65-g002.jpg

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本文引用的文献

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Intern Med. 2016;55(23):3413-3420. doi: 10.2169/internalmedicine.55.7119. Epub 2016 Dec 1.
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Echocardiography in stress cardiomyopathy and acute LVOT obstruction.应激性心肌病和急性左心室流出道梗阻的超声心动图检查。
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