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Takotsubo 综合征的现有知识状况:欧洲心脏病学会心力衰竭协会 Takotsubo 综合征工作组的立场声明。

Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology.

机构信息

National Heart and Lung Institute, Imperial College, London, UK.

NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, UK.

出版信息

Eur J Heart Fail. 2016 Jan;18(1):8-27. doi: 10.1002/ejhf.424. Epub 2015 Nov 9.

DOI:10.1002/ejhf.424
PMID:26548803
Abstract

Takotsubo syndrome is an acute reversible heart failure syndrome that is increasingly recognized in modern cardiology practice. This Position Statement from the European Society of Cardiology Heart Failure Association provides a comprehensive review of the various clinical and pathophysiological facets of Takotsubo syndrome, including nomenclature, definition, and diagnosis, primary and secondary clinical subtypes, anatomical variants, triggers, epidemiology, pathophysiology, clinical presentation, complications, prognosis, clinical investigations, and treatment approaches. Novel structured approaches to diagnosis, risk stratification, and management are presented, with new algorithms to aid decision-making by practising clinicians. These also cover more complex areas (e.g. uncertain diagnosis and delayed presentation) and the management of complex cases with ongoing symptoms after recovery, recurrent episodes, or spontaneous presentation. The unmet needs and future directions for research in this syndrome are also discussed.

摘要

应激性心肌病是一种常见于现代心脏病学实践中的急性可逆性心力衰竭综合征。本欧洲心脏病学会心力衰竭协会立场声明对应激性心肌病的各种临床和病理生理学方面进行了全面综述,包括命名法、定义和诊断、主要和次要临床亚型、解剖变异、诱因、流行病学、病理生理学、临床表现、并发症、预后、临床检查和治疗方法。提出了新的结构化诊断、风险分层和管理方法,以及新的算法来帮助临床医生做出决策。这些还涵盖了更复杂的领域(例如不确定的诊断和延迟出现)以及在恢复后、复发或自发性出现时持续症状、复杂病例的管理。还讨论了该综合征的研究中未满足的需求和未来方向。

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