Baerends Eva P, Boeije Tom, Van Capelle Anna, Mullaart-Jansen Nieke E, Burg Michael D, Bredenoord Albert J
Department of Emergency Medicine, Westfriesgasthuis, Hoorn, the Netherlands.
Department of Emergency Medicine, Noordwest Ziekenhuisgroep, Alkmaar, the Netherlands.
Afr J Emerg Med. 2019 Mar;9(1):41-44. doi: 10.1016/j.afjem.2018.09.005. Epub 2018 Oct 13.
This retrospective case series describes the use of cola to immediately treat complete oesophageal food bolus obstructions in the emergency centre. Short of emergent endoscopy - which is invasive, expensive, not without adverse events, and often unavailable in low-resource settings - no other proven therapies exist to relieve oesophageal food impactions.
We performed a chart review of adults with complete oesophageal food bolus obstructions presenting to two Dutch emergency centres. Our primary outcome was cola's success rate in resolving the obstruction. Our secondary outcome was adverse event occurrence.
We identified 22 cola interventions in 19 patients, the majority of whom (77.3%) were male. The median age was 59 years (IQR 29-73). All presentations were due to meat impaction. Endoscopy revealed relevant upper gastrointestinal pathology in 54.5%. When initiated in the emergency centre, cola successfully resolved 59% of complete oesophageal obstructions. No adverse events were reported in patients successfully treated with cola.
While keenly aware of our retrospective study's limitations, we found a promising success rate for cola as an acute intervention for oesophageal food bolus impactions. We registered no adverse events attributable to cola. Also, given that cola is cheap, widely available and seemingly safe we believe it can be considered in patients with oesophageal obstructions due to food, either as pre-endoscopy treatment or in case endoscopy is not available at all. We think our findings provide an impetus for prospective research on this intervention.
本回顾性病例系列描述了在急诊中心使用可乐立即治疗完全性食管食物团块梗阻的情况。除了紧急内镜检查(具有侵入性、费用高、并非没有不良事件,且在资源匮乏地区往往无法进行)外,不存在其他经证实的缓解食管食物嵌塞的疗法。
我们对两家荷兰急诊中心收治的患有完全性食管食物团块梗阻的成人患者进行了病历回顾。我们的主要结局是可乐解除梗阻的成功率。次要结局是不良事件的发生情况。
我们在19例患者中确定了22次可乐干预,其中大多数患者(77.3%)为男性。中位年龄为59岁(四分位间距29 - 73岁)。所有病例均因肉类嵌塞所致。内镜检查显示54.5%的患者存在相关的上消化道病变。在急诊中心开始使用可乐治疗时,可乐成功解除了59%的完全性食管梗阻。接受可乐成功治疗的患者未报告不良事件。
尽管我们敏锐地意识到本回顾性研究的局限性,但我们发现可乐作为食管食物团块嵌塞的急性干预措施具有可观的成功率。我们未记录到可归因于可乐的不良事件。此外,鉴于可乐价格便宜、广泛可得且看似安全,我们认为对于因食物导致食管梗阻的患者,可以考虑将其作为内镜检查前的治疗方法,或者在根本无法进行内镜检查的情况下使用。我们认为我们的研究结果为对该干预措施进行前瞻性研究提供了动力。