Obasi O E
Br J Dermatol. 1986 May;114(5):597-602. doi: 10.1111/j.1365-2133.1986.tb04067.x.
Two patients with schistosomiasis of the skin were seen at the Ahmadu Bello University Teaching Hospital, Kaduna, Northern Nigeria, between June 1978 and December 1980. The first case was not suspected on clinical grounds, but was diagnosed only after terminally-spined ova of Schistosoma haematobium were found in histological sections of the skin lesions. Both patients were successfully treated with niridazole (Ambilhar). These bring to eight the total number of cases of cutaneous schistosomiasis recorded in Nigeria in the past 40 years, four of which were in indigenous Nigerians. It seems that the high endemicity of the disease confers some degree of natural immunity to the indigenous population, making ectopic forms rare. Clinicians should be aware of the existence of cutaneous forms of the disease and of their excellent response to specific chemotherapy.
1978年6月至1980年12月期间，在尼日利亚北部卡杜纳的阿哈马杜·贝洛大学教学医院，接诊了两名皮肤血吸虫病患者。第一例在临床上未被怀疑，仅在皮肤病变的组织切片中发现埃及血吸虫的终末棘卵后才得以确诊。两名患者均接受硝唑咪（氨苯胍）治疗并获成功。这使尼日利亚过去40年记录的皮肤血吸虫病病例总数增至8例，其中4例为尼日利亚本地人。看来该病的高流行率使本地人群获得了一定程度的自然免疫力，从而使异位形式罕见。临床医生应意识到该病皮肤形式的存在及其对特异性化疗的良好反应。
