Department of Psychiatry, University of California, San Diego, United States of America; VA San Diego Healthcare System, United States of America.
Department of Psychiatry, University of California, San Diego, United States of America; VA San Diego Healthcare System, United States of America.
Addict Behav. 2019 Aug;95:91-97. doi: 10.1016/j.addbeh.2019.03.007. Epub 2019 Mar 7.
Recent data regarding growth in concurrent use of nicotine and marijuana have raised concern that reductions in legal restrictions on marijuana use may increase risk for tobacco-related harms. Previous studies have shown cross-sectional links between use of both substances, but less is known about associations over time. The goal of the present study was to test the hypothesis that there is a bidirectional relationship between use of marijuana and use of tobacco products over time, such that increasing use of either substance would predict increasing use of the other. Participants (n = 391, 52% male) were 18-24 year-old Californians who were non-daily cigarette smokers at enrollment and had never been daily smokers. They reported nicotine/tobacco and marijuana use quarterly over 2 years. Longitudinal negative binomial and logistic regression models indicated that each additional timepoint at which participants reported recent marijuana use predicted 9-11% increases in tobacco quantity and frequency. Additionally, each additional timepoint at which cigarette or tobacco use was reported predicted 19-22% greater marijuana frequency. Data suggest that young adults who use marijuana more frequently are likely at risk for greater tobacco exposure, and vice versa. These findings suggest a need for preventive measures that focus on concurrent use of both substances rather than either individually.
最近有关尼古丁和大麻同时使用增长的数据引起了人们的担忧，即大麻使用的法律限制减少可能会增加与烟草相关的危害风险。先前的研究表明这两种物质的使用之间存在横断面联系，但关于随时间推移的关联知之甚少。本研究的目的是检验这样一个假设，即大麻和烟草制品的使用随时间呈双向关系，即任何一种物质的使用增加都会预测另一种物质的使用增加。参与者（n=391，52%为男性）为 18-24 岁的加利福尼亚人，在入组时是非每日吸烟者，且从未成为每日吸烟者。他们在 2 年内每季度报告尼古丁/烟草和大麻的使用情况。纵向负二项和逻辑回归模型表明，参与者报告最近大麻使用的每个额外时间点都预测烟草数量和频率增加 9-11%。此外，报告吸烟或烟草使用的每个额外时间点都预测大麻使用频率增加 19-22%。数据表明，经常使用大麻的年轻人可能面临更大的烟草暴露风险，反之亦然。这些发现表明需要采取预防措施，重点关注这两种物质的同时使用，而不是单独关注任何一种物质。
