Institute for Social Research, University of Michigan, 426 Thompson St., Ann Arbor, MI 48106-1248, USA.
Institute for Social Research, University of Michigan, 426 Thompson St., Ann Arbor, MI 48106-1248, USA.
Addict Behav. 2024 Nov;158:108109. doi: 10.1016/j.addbeh.2024.108109. Epub 2024 Jul 19.
High-intensity drinking (HID; 10+ drinks/occasion) is associated with acute and long-term risks, including use of other substances. Earlier HID initiation is associated with high-risk alcohol use in young adulthood. Less is known about when HID initiation occurs relative to other substances and how it is associated with subsequent substance use. This study examined survey data from 468 respondents (35.5% female, 65.5% non-Hispanic white) who reported initiating HID by age 20. Weighted descriptive statistics of year of initiation for HID, marijuana, and nicotine were obtained. Weighted linear and logistic regressions examined associations between year and order of HID initiation and age 20 substance use (i.e., nicotine vaping, cigarette use, other tobacco use, marijuana use, marijuana vaping, simultaneous alcohol and marijuana use, and other illicit drug use) and alcohol use disorder (AUD) symptoms. Over half of participants initiated HID after marijuana (54.6%) and nicotine (54.4%). Later HID initiation was associated with fewer AUD symptoms and lower odds of all outcomes except marijuana and other illicit drug use. Initiating HID before marijuana was associated with lower odds of marijuana use outcomes and other illicit drug use at age 20. Initiating HID before nicotine was associated with lower odds of all substance use outcomes at age 20. Earlier HID initiation was associated with risk for subsequent substance use, but initiating HID earlier than other substances was not. Given its association with both alcohol-related outcomes and other substance use in young adulthood, earlier HID initiation is an important target for screening and intervention.
高强度饮酒（HID；每次 10 杯或以上）与急性和长期风险相关，包括使用其他物质。较早的 HID 开始与年轻人时期的高风险酒精使用有关。对于 HID 开始与其他物质的相对时间以及它如何与随后的物质使用相关，人们知之甚少。本研究检查了来自 468 名受访者（女性占 35.5%，非西班牙裔白人占 65.5%）的调查数据，这些受访者报告在 20 岁之前开始 HID。获得了 HID、大麻和尼古丁的起始年份的加权描述性统计数据。加权线性和逻辑回归检验了 HID 起始年份和顺序与 20 岁时物质使用（即尼古丁蒸气、香烟使用、其他烟草使用、大麻使用、大麻蒸气、同时使用酒精和大麻以及其他非法药物使用）和酒精使用障碍（AUD）症状之间的关联。超过一半的参与者在大麻（54.6%）和尼古丁（54.4%）之后开始 HID。较晚的 HID 开始与较少的 AUD 症状和较低的所有结果（除大麻和其他非法药物使用）的几率相关。在大麻之前开始 HID 与 20 岁时大麻使用结果和其他非法药物使用的几率降低相关。在尼古丁之前开始 HID 与 20 岁时所有物质使用结果的几率降低相关。较早的 HID 开始与随后的物质使用相关，但在其他物质之前开始 HID 并不一定。鉴于其与年轻成年人时期的酒精相关结果和其他物质使用的关联，较早的 HID 开始是筛查和干预的重要目标。
