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健康男性在倾斜试验中对直立性晕厥的静脉血浆肾上腺素反应。

Venous plasma adrenaline response to orthostatic syncope during tilting in healthy men.

作者信息

Tatár P, Bulas J, Kvetnanský R, Strec V

出版信息

Clin Physiol. 1986 Jun;6(3):303-9. doi: 10.1111/j.1475-097x.1986.tb00627.x.

DOI:10.1111/j.1475-097x.1986.tb00627.x
PMID:3087688
Abstract

The effect of transient cerebral ischaemia connected with acute orthostatic hypotension on plasma adrenaline and noradrenaline levels was studied in seven healthy male volunteers during tilt. Sublingual administration of 1 mg nitroglycerin was used to block peripheral vascular reflexes and thus to provoke orthostatic intolerance. A consistent increase in plasma adrenaline concentrations (from 19.2 to 104.3 pg/ml on average, P less than 0.01) was found in six subjects who developed clinical signs of collapse after tilting. Plasma adrenaline never changed after tilting without collapse. Posturally stimulated plasma noradrenaline increases were similar yet irrespective of the presence of collapse.

摘要

在7名健康男性志愿者倾斜过程中,研究了与急性直立性低血压相关的短暂性脑缺血对血浆肾上腺素和去甲肾上腺素水平的影响。舌下给予1毫克硝酸甘油以阻断外周血管反射,从而引发直立不耐受。在6名倾斜后出现虚脱临床体征的受试者中,发现血浆肾上腺素浓度持续升高(平均从19.2皮克/毫升升至104.3皮克/毫升,P<0.01)。未发生虚脱的情况下,倾斜后血浆肾上腺素水平从未改变。无论是否发生虚脱,姿势刺激引起的血浆去甲肾上腺素升高相似。

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