Schulz Benjamin L
School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, QLD, Australia.
Methods Mol Biol. 2019;1969:105-112. doi: 10.1007/978-1-4939-9202-7_7.
Mass spectrometry (MS) proteomics allows systematic identification, characterization, and relative quantification of the full suite of proteins in a biological sample, and is a powerful analytical approach for investigation of many aspects of the biology of Neisseria meningitidis. Here, we describe methods for robust and efficient sample preparation of the proteome of N. meningitidis suitable for diverse MS proteomics workflows.
质谱（MS）蛋白质组学能够对生物样品中的全套蛋白质进行系统的鉴定、表征和相对定量，是研究脑膜炎奈瑟菌生物学诸多方面的一种强大分析方法。在此，我们描述了适用于多种MS蛋白质组学工作流程的、对脑膜炎奈瑟菌蛋白质组进行稳健且高效样品制备的方法。
