[烟酸新氨基酸衍生物的催眠和心脏作用特性]
[Antisoporific and cardiotropic properties of new amino acid derivatives of nicotinic acid].
作者信息
Samvelian V M, Kazarian S A, Dzhanpoladian E G, Matevosian L A
出版信息
Farmakol Toksikol. 1986 May-Jun;49(3):35-7.
PMID:3087769
Abstract
On the models of urethane, nembutal and ethyl alcohol sleep it was shown that nicotinoylcapronate, nicotinoylserine and nicotinoylvaline possess antihypnotic properties being superior to those of cordiamine and on some models phenamine. Nicotinoylvaline and nicotinoylalanine normalized the myocardial contraction in animals with experimental ischemia.
摘要
在乌拉坦、戊巴比妥和乙醇致眠模型上的研究表明，烟酰己酸酯、烟酰丝氨酸和烟酰缬氨酸具有抗催眠特性，优于可拉明，在某些模型上也优于苯乙胺。烟酰缬氨酸和烟酰丙氨酸使实验性缺血动物的心肌收缩恢复正常。
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