Salmon H
Ann Immunol (Paris). 1978 Apr-Jun;129 C(4):571-84.
The immunoglobulins obtained from a sheep anti-pig thymocyte serum were made specific for a subpopulation of porcine lymphocytes by adsorptions with pig red blood cells and bone marrow cells. In the presence of rabbit complement, these immunoglobulins killed a porcine lymphocyte subpopulation similar to the subpopulation of lymphocytes forming rosettes with sheep red blood cell (E-rosettes) when enhanced by dextran. Without complement, these immunoglobulins inhibited the E-rosette phenomenon at a dilution near to the cytotoxicity titre of the serum, but did not inhibit the rosettes formed with activated zymosan (ZC rosettes). These two different tests revealed the presence of antibodies directed against pig T-lymphocyte specific antigens and allowed the quantitication of T lymphocytes in different organs.
从羊抗猪胸腺细胞血清中获得的免疫球蛋白，通过用猪红细胞和骨髓细胞吸附，使其对猪淋巴细胞亚群具有特异性。在兔补体存在的情况下，这些免疫球蛋白杀死了一个猪淋巴细胞亚群，该亚群类似于在右旋糖酐增强时与羊红细胞形成玫瑰花结（E-玫瑰花结）的淋巴细胞亚群。在没有补体的情况下，这些免疫球蛋白在接近血清细胞毒性滴度的稀释度下抑制E-玫瑰花结现象，但不抑制与活化酵母聚糖形成的玫瑰花结（ZC玫瑰花结）。这两种不同的试验揭示了针对猪T淋巴细胞特异性抗原的抗体的存在，并允许对不同器官中的T淋巴细胞进行定量。
