Lyne A, Johnson J, Baldwin D
Department of Paediatric Dentistry, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Faculty of Dentistry, Oral & Craniofacial Sciences, Paediatric Dentistry, Centre of Oral Clinical and Translational Science, King's College London, The Strand, London, WC2R 2LS, UK.
Eur Arch Paediatr Dent. 2020 Feb;21(1):25-30. doi: 10.1007/s40368-019-00433-9. Epub 2019 Mar 16.
Inhalation sedation (IHS), using nitrous oxide and oxygen, is a commonly used form of pharmacological behaviour management in paediatric dentistry. Previous studies suggest that IHS causes a delay in reaction time, which recovers to baseline within 10 min.
To observe the reaction times (RT) of children before and after undergoing IHS for dental treatment.
Sixty children from clinics at St Thomas' Hospital (London, UK) participated in this observational study. RT was measured using an eight-point choice reaction time system (MOART computer panel, Lafayette Instruments). RT was measured twice: before (prior to patient entering clinic for treatment) and after (immediately after discharge from the clinic). A paired-samples t test was used to analyse data.
Fifty-two patients completed the study. There was a statistically significant delay in RT after treatment (p = 0.022). There was no significant correlation between RT and concentration of nitrous oxide, or length of the recovery period.
Children may have a small impairment in reaction times following recovery from IHS in the clinical setting, regardless of the strength of nitrous oxide given, or the length of the recovery period. The child's escort should be aware of the need to supervise the child following discharge.
使用一氧化二氮和氧气的吸入镇静(IHS)是儿科牙科中常用的一种药理行为管理形式。先前的研究表明,IHS会导致反应时间延迟,在10分钟内恢复到基线水平。
观察儿童在接受IHS进行牙科治疗前后的反应时间(RT)。
来自英国伦敦圣托马斯医院诊所的60名儿童参与了这项观察性研究。使用八点选择反应时间系统(MOART计算机面板,拉斐特仪器公司)测量RT。RT测量两次:治疗前(患者进入诊所治疗前)和治疗后(从诊所出院后立即测量)。采用配对样本t检验分析数据。
52名患者完成了研究。治疗后RT有统计学意义的延迟(p = 0.022)。RT与一氧化二氮浓度或恢复期长度之间无显著相关性。
在临床环境中,儿童从IHS恢复后反应时间可能会有轻微损害,无论给予的一氧化二氮强度或恢复期长度如何。儿童的陪同人员应意识到在出院后需要对儿童进行监督。