Bhat Alina, Neculiseanu Elvira, Tam Eric L, Gendy Adam, Beckles Daniel L, Luhrs Carol, Braverman Albert
a Downstate College of Medicine, Department of Medicine, Division of Hematology-Oncology , State University of New York , Brooklyn , NY , USA.
b Downstate College of Medicine, Department of Surgery, Division of Cardiothoracic Surgery , State University of New York , Brooklyn , NY , USA.
Hemoglobin. 2019 Jan;43(1):1-3. doi: 10.1080/03630269.2019.1579736. Epub 2019 Mar 18.
Purulent pericarditis is a localized infection with a thick, fibrinous hypercellular exudate and is historically associated with a high mortality. We describe a case of purulent pericarditis due to in a 30-year-old woman with sickle cell disease who presented with fever, dyspnea, and septicemia. Despite timely initiation of antibiotics, she developed a large purulent pericardial effusion requiring surgical pericardiocentesis followed by a pericardial window. At 14 months follow-up, she has remained asymptomatic without sequelae. A review of the literature contained only four patients with purulent pericarditis in sickle cell patients. We discuss the unique aspects of this case in the context of purulent pericarditis in the age of modern antibiotics and hypothesize on the pathogenesis of delayed pericardial effusion after pericarditis.
化脓性心包炎是一种伴有浓稠、纤维蛋白性细胞增多渗出物的局部感染，历来死亡率较高。我们描述了一例30岁镰状细胞病女性因[病因未提及]导致的化脓性心包炎病例，该患者出现发热、呼吸困难和败血症。尽管及时开始使用抗生素，但她仍出现大量化脓性心包积液，需要进行外科心包穿刺术，随后行心包开窗术。在14个月的随访中，她一直无症状，无后遗症。文献综述仅发现4例镰状细胞病患者发生化脓性心包炎。我们在现代抗生素时代化脓性心包炎的背景下讨论该病例的独特之处，并对心包炎后延迟性心包积液的发病机制进行推测。
