Pope H G, Hudson J I
J Clin Psychiatry. 1986 Jul;47(7):339-45.
More than 30 reports, including 9 placebo-controlled, double-blind studies, have assessed the efficacy of various medications, mostly antidepressants, for the treatment of bulimia. A critical review of the available data suggests that antidepressants, and possibly other thymoleptic agents, are clearly superior to placebo for the treatment of bulimia; the studies have not identified specific subgroups of bulimic patients who are, or are not, candidates for these agents; and tentatively, these agents may benefit major affective disorder and bulimia via similar mechanisms.
30 多篇报告，包括 9 项安慰剂对照的双盲研究，评估了各种药物（主要是抗抑郁药）治疗贪食症的疗效。对现有数据的批判性综述表明，抗抑郁药以及可能的其他心境稳定剂在治疗贪食症方面明显优于安慰剂；这些研究尚未确定哪些贪食症患者亚组适合或不适合使用这些药物；初步来看，这些药物可能通过类似机制对重度情感障碍和贪食症有益。
