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产前社会支持对婴儿生命最初 18 个月肥胖的保护作用。

The Protective Effect of Prenatal Social Support on Infant Adiposity in the First 18 Months of Life.

机构信息

Division of General Pediatrics, Department of Pediatrics, New York University School of Medicine, New York, NY.

Division of General Pediatrics, Department of Pediatrics, New York University School of Medicine, New York, NY.

出版信息

J Pediatr. 2019 Jun;209:77-84. doi: 10.1016/j.jpeds.2019.02.017. Epub 2019 Mar 14.

DOI:10.1016/j.jpeds.2019.02.017
PMID:30879731
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6535345/
Abstract

OBJECTIVE

To determine whether prenatal social support was associated with infant adiposity in the first 18 months of life in a low-income, Hispanic sample, known to be at high risk of early child obesity.

STUDY DESIGN

We performed a longitudinal analysis of 262 low-income, Hispanic mother-infant pairs in the control group of the Starting Early child obesity prevention trial. Prenatal social support was measured using an item from the Maternal Social Support Index. We used multilevel modeling to predict weight-for-length z-score trajectories from birth to age 18 months and logistic regression to predict macrosomia and overweight status at ages 6, 12, and 18 months.

RESULTS

High prenatal social support was independently associated with lower infant adiposity trajectories from birth to age 18 months (B = -0.40; 95% CI, -0.63 to -0.16), a lower odds of macrosomia (aOR = 0.35; 95% CI, 0.15-0.80), and a lower odds of overweight at ages 12 (aOR = 0.28; 95% CI, 0.10-0.74) and 18 months (aOR = 0.35; 95% CI, 0.14-0.89). Prenatal social support was not significantly associated with overweight status at age 6 months.

CONCLUSIONS

Prenatal social support may protect against excessive infant adiposity and overweight in low-income, Hispanic families. Further research is needed to elucidate mechanisms underlying these associations and to inform preventive strategies beginning in pregnancy.

摘要

目的

在一个已知有发生儿童早期肥胖高风险的低收入西班牙裔人群中,确定产前社会支持与婴儿生命最初 18 个月的肥胖之间的关系。

研究设计

我们对起始早期儿童肥胖预防试验对照组中的 262 对低收入西班牙裔母婴进行了纵向分析。产前社会支持使用来自母亲社会支持指数的一个项目进行测量。我们使用多层建模来预测从出生到 18 个月时体重长度 z 评分轨迹,并使用逻辑回归来预测 6、12 和 18 个月时的巨大儿和超重状态。

结果

高产前社会支持与从出生到 18 个月时婴儿肥胖轨迹独立相关(B = -0.40;95%置信区间,-0.63 至-0.16),巨大儿的可能性降低(aOR = 0.35;95%置信区间,0.15-0.80),12 个月(aOR = 0.28;95%置信区间,0.10-0.74)和 18 个月(aOR = 0.35;95%置信区间,0.14-0.89)时超重的可能性降低。产前社会支持与 6 个月时的超重状态无显著相关性。

结论

产前社会支持可能对低收入西班牙裔家庭中婴儿肥胖和超重起到保护作用。需要进一步研究阐明这些关联的机制,并为从妊娠开始的预防策略提供信息。

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