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Incidence and outcomes of eclampsia: a single-center 30-year study.

作者信息

Uludag Semih Zeki, Gokmen Karasu Ayse Filiz, Kutuk Mehmet Serdar, Takmaz Taha

机构信息

a Department of Obstetrics and Gynecology , Erciyes University Medical Faculty , Kayseri , Turkey.

b Department of Obstetrics and Gynecology , Bezmialem Vakif University Medical Faculty , Istanbul , Turkey.

出版信息

Hypertens Pregnancy. 2019 May;38(2):119-123. doi: 10.1080/10641955.2019.1590719. Epub 2019 Mar 17.

DOI:10.1080/10641955.2019.1590719
PMID:30880504
Abstract

OBJECTIVE

We aimed to determine the incidence of eclampsia at Erciyes University Hospital which is a tertiary referral center situated at central Anatolia. Additionally, we investigated eclampsia-associated maternal and perinatal outcomes for the 30-year study period.

METHODS

A retrospective review was performed for all women who were diagnosed with eclampsia and admitted to the Erciyes University Medical School, Department of Obstetrics and Gynecology from January 1985 to December 2015. Improvement in management gained over time was determined by comparing the results of the years 2005-2015 with data which were already published from years 1985-1999 and 2000-2004.

RESULTS

Eclampsia prevalence was 289/46,928 (% 0.61). Maternal age at the time of diagnosis did not differ statistically; however, gestational age at diagnosis and birth weight decreased significantly throughout the years (p < 0.005). The perinatal mortality rate showed a slight decrease throughout the years (p = 0.238). Maternal mortality rate also decreased throughout the years; it was 1.7% in 2005-2009 and 0 % in 2010-2015 (p = 0.246).

CONCLUSION

The prevalence of eclampsia cases has decreased over the years. Maternal mortality attributed to eclampsia has also declined. The early diagnosis and treatment of eclampsia have resulted in the increase of premature deliveries. The perinatal mortality rate showed a slight decrease throughout the years (p = 0.238); however, it is not at a desirable rate compared to developed countries.

摘要

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