Sebastian Sujeesh, Malhotra Rajesh, Dhawan Benu
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.
Indian J Med Microbiol. 2018 Oct-Dec;36(4):475-487. doi: 10.4103/ijmm.IJMM_19_11.
Total joint arthroplasty (TJA) is one of the most common and reliable orthopaedic procedures that has significantly improved the quality of life of patients with degenerative joint diseases. Following the increase in the ageing population, availability of trained orthopaedic surgeons and advances in implantation procedures, demand for TJA both globally and in India is significantly increasing. Though TJA is one of the most cost-successful orthopaedic procedures, prosthetic joint infection (PJI) is one of the major complications of joint arthroplasty. Accurate diagnosis of PJI is challenging. Since total hip and knee arthroplasties comprises the majority of TJAs, this review focuses on the current understanding of incidence, risk factors, pathogenesis, causative microorganisms, diagnosis, treatment and prevention of PJI related to these two procedures.
全关节置换术（TJA）是最常见且可靠的骨科手术之一，显著提高了退行性关节疾病患者的生活质量。随着老龄化人口增加、训练有素的骨科外科医生数量增多以及植入手术技术的进步，全球和印度对TJA的需求都在显著增长。尽管TJA是最具成本效益的骨科手术之一，但假体关节感染（PJI）是关节置换术的主要并发症之一。PJI的准确诊断具有挑战性。由于全髋关节和膝关节置换术占TJA的大部分，本综述聚焦于目前对与这两种手术相关的PJI的发病率、危险因素、发病机制、致病微生物、诊断、治疗及预防的认识。
