Mora Annalee
Primary Care/Urgent Care, Medical Center Health System ProCare, Odessa, USA.
Cureus. 2022 Jun 7;14(6):e25712. doi: 10.7759/cureus.25712. eCollection 2022 Jun.
Sepsis is significantly associated with increased mortality among hospitalized patients. Patients can deteriorate rapidly, leading to septic shock (i.e., tissue hypoperfusion and organ dysfunction despite fluid resuscitation that can ultimately require a vasopressor). Patients immunocompromised from medical conditions such as rheumatoid arthritis with multiple joint arthroplasties are at a major risk of increased infections. Equally, medications that impair the immune system's normal function make this clinical case challenging. As noted in this case of a patient with a complex medical history and nontypical sepsis presentation, early intervention and a multidisciplinary approach to patient care is vital to patient improvement and survival during septic shock.
脓毒症与住院患者死亡率增加显著相关。患者病情可能迅速恶化，导致感染性休克（即尽管进行了液体复苏，仍出现组织灌注不足和器官功能障碍，最终可能需要使用血管活性药物）。患有类风湿关节炎并接受多次关节置换术等疾病而免疫功能低下的患者，感染风险大幅增加。同样，损害免疫系统正常功能的药物也使这种临床情况具有挑战性。正如这个具有复杂病史和非典型脓毒症表现的患者案例所示，早期干预和多学科的患者护理方法对于感染性休克患者的病情改善和生存至关重要。
