Villegas Victor M, Wu Shuo-Chieh, Murray Timothy G, Cavuoto Kara M, Capo Hilda, McKeown Craig A
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, FL, USA,
Miami Ocular Oncology and Retina, Miami, FL, USA,
Clin Ophthalmol. 2019 Feb 25;13:431-435. doi: 10.2147/OPTH.S195145. eCollection 2019.
The main purpose of this study was to investigate refractive errors in children with unilateral and bilateral retinoblastoma (RB).
An institutional review board-approved consecutive retrospective cohort study was undertaken. Subjects underwent examination under general anesthesia as part of their RB follow-up, which included evaluation by a single pediatric ophthalmologist. Cycloplegic retinoscopy was performed and keratometry data assessed with a handheld Retinomax K Plus 3 keratorefractometer (Righton Ophthalmic Instruments).
The study included 61 eyes of 37 subjects, with 18 (49%) males and 19 females. Seventeen eyes (28%) had hyperopia with spherical equivalent ≥3 D. Refractive astigmatism ≥1.5 D was present in 32% of all eyes. Nine (38%) subjects had anisometropia ≥2 D. Fifteen (63%) subjects had anisometropia ≥1 D.
This study reports the high proportion of amblyogenic refractive risk factors in children with RB, both in RB-affected eyes and contralateral normal eyes.
本研究的主要目的是调查单侧和双侧视网膜母细胞瘤（RB）患儿的屈光不正情况。
开展一项经机构审查委员会批准的连续回顾性队列研究。作为RB随访的一部分，受试者在全身麻醉下接受检查，其中包括由一名小儿眼科医生进行评估。进行了睫状肌麻痹验光，并使用手持Retinomax K Plus 3角膜屈光计（Righton眼科仪器公司）评估角膜曲率数据。
该研究纳入了37名受试者的61只眼，其中男性18名（49%），女性19名。17只眼（28%）有等效球镜度≥3 D的远视。所有眼中32%存在≥1.5 D的屈光性散光。9名（38%）受试者有≥2 D的屈光参差。15名（63%）受试者有≥1 D的屈光参差。
本研究报告了RB患儿中致弱视性屈光危险因素的比例较高，在受RB影响的眼睛和对侧正常眼睛中均如此。
