Vogel H P, Ketsche R
J Neurol. 1986 Jun;233(3):149-52. doi: 10.1007/BF00314421.
Thirteen drug-free and not severely affected patients with idiopathic Parkinson's disease underwent an insulin-hypoglycaemia test, a TRH test and a levodopa test. The responses of growth hormone, prolactin, cortisol and thyrotropin were measured, and retested under stable therapy with levodopa and benserazide. Mean basal and stimulated hormonal concentrations were in the normal range before and during therapy. Minor abnormalities were observed in individual cases, but did not indicate a hypothalamic dopamine deficit.
13名未使用药物且病情未严重恶化的特发性帕金森病患者接受了胰岛素低血糖试验、促甲状腺激素释放激素（TRH）试验和左旋多巴试验。测量了生长激素、催乳素、皮质醇和促甲状腺激素的反应，并在左旋多巴和苄丝肼稳定治疗下进行了重新测试。治疗前和治疗期间，平均基础和刺激后的激素浓度均在正常范围内。个别病例观察到轻微异常，但未表明存在下丘脑多巴胺缺乏。
