Landa V A, Popova M M, Shimkevich L L, Baranov V K
Biull Eksp Biol Med. 1978 Sep;86(9):361-2.
Experiments were conducted on rabbits. Changes in ATP in the regenerating bone tissue after incomplete osteotomy and removal of a bone section, and also in cases of reparative osteogenesis stimulation in the region of the bone defect by means of pulse electric current were studied. ATP content in the bone callus after incomplete osteotomy and electrostimulation proved to exceed such in the regenerating bone tissue following removal of the bone fragment when no stimulation was applied. On the basis of the data obtained it is suggested that improvement of energy provision of the fracture consolidation process was one of the important links in the mechanism of stimulating influence of the electric current on the reparative regeneration of the bone tissue.
在兔子身上进行了实验。研究了不完全截骨并去除骨段后再生骨组织中三磷酸腺苷(ATP)的变化,以及通过脉冲电流刺激骨缺损区域修复性骨生成情况下的ATP变化。结果证明,不完全截骨和电刺激后骨痂中的ATP含量超过了去除骨碎片且未施加刺激时再生骨组织中的ATP含量。根据所获得的数据表明,改善骨折愈合过程的能量供应是电流对骨组织修复性再生产生刺激作用机制中的重要环节之一。