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[电流对骨组织修复性再生的刺激作用机制]

[Mechanism of the stimulating effect of an electric current on reparative regeneration of bone tissue].

作者信息

Landa V A, Popova M M, Shimkevich L L, Baranov V K

出版信息

Biull Eksp Biol Med. 1978 Sep;86(9):361-2.

PMID:308822
Abstract

Experiments were conducted on rabbits. Changes in ATP in the regenerating bone tissue after incomplete osteotomy and removal of a bone section, and also in cases of reparative osteogenesis stimulation in the region of the bone defect by means of pulse electric current were studied. ATP content in the bone callus after incomplete osteotomy and electrostimulation proved to exceed such in the regenerating bone tissue following removal of the bone fragment when no stimulation was applied. On the basis of the data obtained it is suggested that improvement of energy provision of the fracture consolidation process was one of the important links in the mechanism of stimulating influence of the electric current on the reparative regeneration of the bone tissue.

摘要

在兔子身上进行了实验。研究了不完全截骨并去除骨段后再生骨组织中三磷酸腺苷(ATP)的变化,以及通过脉冲电流刺激骨缺损区域修复性骨生成情况下的ATP变化。结果证明,不完全截骨和电刺激后骨痂中的ATP含量超过了去除骨碎片且未施加刺激时再生骨组织中的ATP含量。根据所获得的数据表明,改善骨折愈合过程的能量供应是电流对骨组织修复性再生产生刺激作用机制中的重要环节之一。

相似文献

1
[Mechanism of the stimulating effect of an electric current on reparative regeneration of bone tissue].[电流对骨组织修复性再生的刺激作用机制]
Biull Eksp Biol Med. 1978 Sep;86(9):361-2.
2
[Adenosine triphosphoric acid in the regenerating bone tissue after electric stimulation of reparative osteogenesis].[电刺激促进修复性骨生成后再生骨组织中的三磷酸腺苷]
Ortop Travmatol Protez. 1978 May(5):15-8.
3
[Electron microscopic study of reparative osteogenesis following electric stimulation of bony tissue regeneration].[电刺激骨组织再生后修复性骨生成的电子显微镜研究]
Biull Eksp Biol Med. 1981 Jun;91(6):719-22.
4
[Effect of direct current on bone regeneration].[直流电对骨再生的影响]
Acta Chir Acad Sci Hung. 1978;19(4):383-92.
5
[Citrate metabolism during the consolidation of experimental fractures].[实验性骨折愈合过程中的柠檬酸盐代谢]
Vopr Med Khim. 1986 Sep-Oct;32(5):44-7.
6
Bioelectric effects of a constant current on fracture callus.恒定电流对骨折骨痂的生物电效应。
Biomed Sci Instrum. 1983;19:53-5.
7
Structure of the osseous callus formed under electric stimulation. An experimental histological study.电刺激下形成的骨痂结构。一项实验组织学研究。
Morphol Embryol (Bucur). 1985 Jan-Mar;31(1):55-9.
8
[Blood flow changes in regenerating bone tissue during electrostimulation for reparative osteogenesis].[电刺激促进修复性骨生成过程中再生骨组织的血流变化]
Ortop Travmatol Protez. 1980 Aug(8):8-10.
9
[Effect of opiod peptides on free radical oxidation in a bone regenerate after fracture].
Patol Fiziol Eksp Ter. 2005 Jan-Mar(1):19-20.
10
[Use of electric stimulation for activating the process of bone consolidation].[使用电刺激激活骨愈合过程]
Med Tekh. 1986 Nov-Dec(6):13-9.