Mikhaĭlova L N, Landa V A
Biull Eksp Biol Med. 1981 Jun;91(6):719-22.
Electron microscopy was used to study the regenerating bone tissue in experimental resection of the diaphysis fragment of the rabbit radius under osteogenesis stimulation by means of pulsed low-frequency electric current. Proliferation and differentiation of fibroblasts and osteoblasts of the bone regenerating tissue were more active under electric stimulation. Hypertrophy and hyperplasia of cell organelles occurred earlier as compared with control. Cell secretion was found to be intensified, manifesting by output of greater amounts of collagen protein. As a result of changes listed, the newly formed bone tissue rapidly filled the defect between the fragments.
采用电子显微镜研究在脉冲低频电流刺激成骨作用下,兔桡骨骨干片段实验性切除后再生骨组织的情况。在电刺激下,骨再生组织中成纤维细胞和成骨细胞的增殖与分化更为活跃。与对照组相比,细胞器的肥大和增生出现得更早。发现细胞分泌增强,表现为大量胶原蛋白的输出。由于上述变化,新形成的骨组织迅速填充了片段之间的缺损。