仿生刺激响应纳米通道及其应用。

Biomimetic stimuli-responsive nanochannels and their applications.

机构信息

Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry, Beihang University, Beijing, P. R. China.

出版信息

Electrophoresis. 2019 Aug;40(16-17):2058-2074. doi: 10.1002/elps.201800536. Epub 2019 Mar 27.

DOI:10.1002/elps.201800536

PMID:30883823

Abstract

Biomimetic smart nanochannels have been studied extensively to achieve the precise ionic transport compared to biological ion channels. Similar to ion channels in living organisms, biomimetic smart nanochannels can respond to various stimuli, which allows for promising applications in many fields. In this review, we mainly summarize the recent advances in the design of biomimetic stimuli-responsive nanochannels and their potential applications including biosensors and drug delivery. Finally, an outlook on the challenges and opportunities for biomimetic stimuli-responsive nanochannels is provided.

摘要

仿生智能纳米通道在精确离子传输方面的研究已经非常广泛，可与生物离子通道相媲美。与生物体内的离子通道类似，仿生智能纳米通道可以对各种刺激做出响应，这使得它们在许多领域有很有前景的应用。在这篇综述中，我们主要总结了仿生刺激响应纳米通道的设计及其在生物传感器和药物输送等方面的潜在应用的最新进展。最后，对仿生刺激响应纳米通道面临的挑战和机遇进行了展望。